Role of plant alkaloids on human health: A review of biological activities

被引：214
作者：
Debnath, Bikash [1 ]
Singh, Waikhom Somraj [1 ]
Das, Manik [1 ]
Goswami, Sanchari [1 ]
Singh, Mahesh Kumar [2 ]
Maiti, Debasish [3 ]
Manna, Kuntal [1 ]
机构：
[1] Tripura Univ, Dept Pharm, Suryamaninagar 799022, Tripura, India
[2] Tripura Univ, Dept Chem, Suryamaninagar 799022, Tripura, India
[3] Tripura Univ, Dept Human Physiol, Suryamaninagar 799022, Tripura, India
来源：
MATERIALS TODAY CHEMISTRY | 2018年 / 9卷
关键词：
Marketed alkaloids; Experimental alkaloids; Biological activity; CENTRAL-NERVOUS-SYSTEM; PERFORMANCE LIQUID-CHROMATOGRAPHY; 2 HYDROXYLATED METABOLITES; IN-VITRO METABOLISM; MAJOR METABOLITES; PHARMACOLOGICAL EVALUATION; PYRROLIZIDINE ALKALOIDS; MASS-SPECTROMETRY; DOSE-RESPONSE; HUMAN URINE;
D O I：
10.1016/j.mtchem.2018.05.001
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Alkaloids are plant secondary metabolite. They are well known nitrogen-containing natural bioactive compounds. Cutting edge research is going on alkaloids to unravel novel therapeutic approaches. Literature reveals that alkaloids contribute multiple biological activities and some alkaloids transform into active metabolites too. In this review, we have focused on marketed and experimental alkaloids. We have summarized sources and biological activities of reported alkaloids in past decades. (C) 2018 Elsevier Ltd. All rights reserved.
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页码：56 / 72
页数：17
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