The study examined stress coping strategies, perceived organizational support and marital status as predictors of work-life balance. Two hundred and fifty-four bank workers participated in the study. Results of the regression analyses showed that stress coping strategies was a significant predictor of work-life balance (beta = .34, p = .000) and contributed 11 % variance in work-life balance after controlling for the effects of gender, age and education. The result further revealed that perceived organizational support significantly predicted workers' work-life balance (beta = .22, p = .001) and contributed additional 4 % variance in work-life balance after the effects of gender, age, education and coping strategies have been controlled. Marital status was not related to work-life balance. The findings of the study were discussed based on Nigerian socio-economic realities. The implications of the findings to work-life policies and practices were discussed.