Smart Process Manufacturing for Formulated Products

被引:17
作者
Litster, James [1 ]
Bogle, Ian David L. [2 ]
机构
[1] Univ Sheffield, Dept Chem & Biol Engn, Sheffield S10 2TN, S Yorkshire, England
[2] UCL, Dept Chem Engn, Ctr Proc Syst Engn, London WC1E 6BT, England
关键词
Smart manufacturing; Formulated products; Pharmaceuticals; Modeling; Supply chain integration; Uncertainty; WET GRANULATION; OPTIMIZATION; DESIGN; UNCERTAINTY; CHALLENGES; MODEL; PERFORMANCE; FRAMEWORK; SYSTEMS;
D O I
10.1016/j.eng.2019.02.014
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
We outline the smart manufacturing challenges for formulated products, which are typically multicomponent, structured, and multiphase. These challenges predominate in the food, pharmaceuticals, agricultural and specialty chemicals, energy storage and energetic materials, and consumer goods industries, and are driven by fast-changing customer demand and, in some cases, a tight regulatory framework. This paper discusses progress in smart manufacturing-namely, digitalization and the use of large data-sets with predictive models and solution-finding algorithms-in these industries. While some progress has been achieved, there is a strong need for more demonstration of model-based tools on realistic problems in order to demonstrate their benefits and highlight any systemic weaknesses. (C) 2019 THE AUTHORS. Published by Elsevier LTD on behalf of Chinese Academy of Engineering and Higher Education Press Limited Company.
引用
收藏
页码:1003 / 1009
页数:7
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