Solid-phase synthesis of oligonucleotides containing a bipyridine ligand at the 3′-3′ inversion of polarity site

被引:3
作者
Galeone, A [1 ]
Mayol, L [1 ]
Oliviero, G [1 ]
Rigano, D [1 ]
Varra, M [1 ]
机构
[1] Univ Naples Federico II, Dip Chim Sostanze Nat, I-80131 Naples, Italy
关键词
D O I
10.1016/S0960-894X(00)00673-9
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The preparation of a solid support useful for the synthesis of oligonucleotides with a 3'-3' inversion of polarity, via a linker containing a chelating molecule, namely 2,2'-bipyridine, is described. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:383 / 386
页数:4
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