A new natural quaternary indole alkaloid isolated from Tabernaemontana laeta Mart. (Apocynaceae)

被引：16

作者：

Medeiros, WLB

Vieira, IJC

Mathias, L

Braz-Filho, R ^{[1
]}

Schripsema, J

机构：

[1] Univ Estadual Norte Fluminense, Setor Quim Prod Nat, BR-28015620 Campos Dos Goytacazes, RJ, Brazil

[2] Univ Fed Rural Rio de Janeiro, Dept Quim, BR-23851970 Seropedica, RJ, Brazil

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2001年 / 12卷 / 03期

关键词：

Tabernaemontana laeta; Apocynaceae; indole-alkaloids; triterpenes;

D O I：

10.1590/S0103-50532001000300008

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new natural quaternary alkaloid, N-b-methylvoachalotine (1), was obtained from the root bark of Tabernaemontana laeta together with three dimeric indole alkaloids, conodurine (2), voacamine (3) and tabernamine (4), and the monomeric indole alkaloids 19S-heyneanine (5), coronaridine (6) and voacangine (7). The known triterpenes alpha -amyrin acetate, beta -amyrin acetate, lupeol acetate and taraxasterol acetate and the phytosterol beta -sitosterol and its 3-O-beta -D-glucoside were also identified. The structures of the compounds were elucidated based on spectroscopic studies.

引用

页码：368 / 372

页数：5

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