Tomato juice inhibits adenosine deaminase activity in human prostate tissue from patient with prostate cancer

被引:3
作者
Durak, I [1 ]
Biri, H
Avci, A
Sözen, S
Devrim, E
机构
[1] Ankara Univ, Fac Med, Dept Biochem, TR-06100 Ankara, Turkey
[2] Gazi Univ, Fac Med, Dept Urol, Ankara, Turkey
关键词
tomato; prostate cancer; adenosine deaminase;
D O I
10.1016/S0271-5317(03)00115-5
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Investigation of possible effects of tomato juice on adenosine deaminase (ADA) activity in prostate tissue from cancer patients was aimed in this study. Ten prostate tissues from patients with pathologically proven localised prostate cancer (Gleason scores 4 to 7) were used in the study. In the tissues, ADA activities with and without preincubation with different amounts of tomato juice were performed. Tomato juice causes significant inhibition on ADA activity in the prostate tissues. Protective effect proposed for tomato against prostate cancer may result from its inhibition potential on ADA. (C) 2003 Elsevier Inc. All rights reserved.
引用
收藏
页码:1183 / 1188
页数:6
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