Exercise Training after Myocardial Infarction Attenuates Dysfunctional Ventricular Remodeling and Promotes Cardiac Recovery

被引：5

作者：

Liu, Shuqing ^{[1
,2
]}

Meng, Xinxiu ^{[1
,2
]}

Li, Guoping ^{[3
,4
]}

Gokulnath, Priyanka ^{[3
,4
]}

Wang, Jing ^{[1
,2
]}

Xiao, Junjie ^{[1
,2
]}

机构：

[1] Shanghai Univ, Peoples Hosp Nantong 6, Sch Med, Inst Geriatr,Affiliated Nantong Hosp, Nantong 226011, Jiangsu, Peoples R China

[2] Shanghai Univ, Shanghai Engn Res Ctr Organ Repair, Sch Life Sci, Inst Cardiovasc Sci,Cardiac Regenerat & Ageing La, Shanghai 200444, Peoples R China

[3] Massachusetts Gen Hosp, Cardiovasc Div, Boston, MA 02114 USA

[4] Harvard Med Sch, Boston, MA 02114 USA

来源：

REVIEWS IN CARDIOVASCULAR MEDICINE | 2022年 / 23卷 / 04期

基金：

中国国家自然科学基金;

关键词：

exercise training; ventricular remodeling; microRNA; myocardial Infarction; ISCHEMIA-REPERFUSION INJURY; ACUTE CARDIOVASCULAR EVENTS; AMERICAN-HEART-ASSOCIATION; NITRIC-OXIDE; PHYSICAL-ACTIVITY; SCIENTIFIC STATEMENT; CURRENT KNOWLEDGE; SKELETAL-MUSCLE; LIPID-METABOLISM; DOWN-REGULATION;

D O I：

10.31083/j.rcm2304148

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Recent evidences have shown that exercise training not only plays a necessary role in maintaining cardiac homeostasis, but also pro-motes cardiac repair after myocardial infarction. Post-myocardial infarction, exercise training has been observed to effectively increase the maximum cardiac output, and protect myocardial cells against necrosis and apoptosis, thus leading to an improved quality of life of myocardial infarction patients. In fact, exercise training has received more attention as an adjunct therapeutic strategy for both treat-ment and prevention of myocardial infarction. This review summarizes the experimental evidence of the effects of exercise training in ventricular remodeling after myocardial infarction, and tries to provide theoretical basis along with suitable references for the exercise prescription aimed at prevention and therapy of myocardial infarction.

引用

页数：14

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