Human placenta as an endocrine organ

被引：85

作者：

Evain-Brion, D ^{[1
]}

Malassine, A ^{[1
]}

机构：

[1] Fac Sci Pharmaceut & Biol Paris, U427, INSERM, F-75006 Paris, France

来源：

GROWTH HORMONE & IGF RESEARCH | 2003年 / 13卷

关键词：

syncytiotrophoblast; endocrine; trophoblast; cytotrophoblast; placenta; human chorionic gonadotropin; chorionic villus;

D O I：

10.1016/S1096-6374(03)00053-4

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The placenta is a unique, autonomous and transient organ. It ensures maternal-fetal exchanges and is also involved in maternal tolerance of feto-paternal antigens. The human placenta is characterized by the major invasion of the trophoblast, which comes in contact with the maternal blood, and by the intensity and the specificity of its endocrine functions. Placental hormones are required for the establishment and maintenance of pregnancy, adaptation of the maternal organism to pregnancy, fetal growth and well being, and development of the mechanisms involved in parturition. The endocrine tissue of the placenta is the syncytiotrophoblast, which covers the chorionic villi, and arises from the fusion of the cytotrophoblasts. In this review we will summarize the particulars of human syncytiotrophoblast development and endocrine functions. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：S34 / S37

页数：4

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