Copolymers containing functional groups intrinsic to the active centers of serine hydrolases: Synthesis and evaluation of catalytic capability

被引：1

作者：

Lozinsky, V. I. ^{[1
]}

Zaborina, O. E. ^{[1
]}

Klimova, T. P. ^{[1
]}

Babushkina, T. A. ^{[1
]}

Kovaleva, A. S. ^{[2
]}

Boltukhina, E. V. ^{[2
]}

Chernyshev, V. P. ^{[2
]}

Burova, T. V. ^{[1
]}

Grinberg, N. V. ^{[1
]}

Grinberg, V. Ya. ^{[1
]}

Khokhlov, A. R. ^{[1
]}

机构：

[1] Russian Acad Sci, AN Nesmeyanov Organoelement Cpds Inst, Ul Vavilova 28, Moscow 119991, Russia

[2] AO Shchelkovo Agrokhim, Zavodskaya Ul 2, Shchelkovo 141101, Moscow Oblast, Russia

来源：

POLYMER SCIENCE SERIES B | 2016年 / 58卷 / 01期

关键词：

CONFORMATION-DEPENDENT DESIGN; PROTEIN-LIKE COPOLYMERS; N-VINYLCAPROLACTAM POLYMERS; VINYLIMIDAZOLE COPOLYMERS; TRANSITIONS; ENERGETICS; BEHAVIOR;

D O I：

10.1134/S156009041601005X

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

N-Acryloyl derivatives of histamine, monoethanolamine, and beta-alanine, which contain imidazole, hydroxyl, and carboxyl functional groups, respectively, are synthesized and characterized. Copolymers, which are further divided into thermally precipitable and thermally nonprecipitable (soluble) fractions, are obtained via the free-radical copolymerization of N-vinylcaprolactam and the specified comonomers that is initiated by a persulfate-tertiary amine redox system in a medium of 10% aqueous dimethyl sulfoxide (DMSO) at 65A degrees C. It is shown that the soluble fractions of the synthesized copolymers exhibit catalytic activity in the reaction of hydrolysis of 4-nitrophenyl propionate (NPP) at a temperature above the coil-to-globule transition.

引用

页码：27 / 37

页数：11

共 25 条

[21] Synthesis and characterization of novel copolymers containing pendant amine functional groups based on D, L-lactide, glycolide and poly(peg-co-L-aspartic acid)
Luo, BH
Quan, DP
Liao, KR
Lu, ZJ
Zhou, CR
ACTA POLYMERICA SINICA, 2005, (03): : 327 - 332
[22] Membrane-Active Thermoresponsive Block Copolymers Containing a Diacylglycerol-Based Segment: RAFT Synthesis, Doxorubicin Encapsulation, and Evaluation of Cytotoxicity against Breast Cancer Cells
Kurowska, Izabela
Markiewicz, Karolina H.
Niemirowicz-Laskowska, Katarzyna
Destarac, Mathias
Wielgat, Przemyslaw
Misztalewska-Turkowicz, Iwona
Misiak, Pawel
Car, Halina
Wilczewska, Agnieszka Z.
BIOMACROMOLECULES, 2023, 24 (11) : 4854 - 4868
[23] Ruthenium(II) complexes containing optically active hemilabile P,N,O-tridentate ligands. Synthesis and evaluation in catalytic asymmetric transfer hydrogenation of acetophenone by propan-2-ol
Yang, H
AlvarezGressier, M
Lugan, N
Mathieu, R
ORGANOMETALLICS, 1997, 16 (07) : 1401 - 1409
[24] Synthesis and characterization of poly(N-acyl or N-aroyl ethylenimines) containing various pendant functional groups .5. Random copolymers of 4-allyloxy and 4-methoxy phenyl oxazolines and their adducts with mercaptoacetic acid
Cai, GF
Litt, MH
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 1996, 34 (13) : 2719 - 2727
[25] Synthesis and characterization of poly(N-acyl or N-aroyl ethylenimines) containing various pendant functional groups. V. Random copolymers of 4-allyloxy and 4-methoxy phenyl oxazolines and their adducts with mercaptoacetic acid
Case Western Reserve Univ, Cleveland, United States
J Polym Sci Part A, 13 (2719-2727):

← 1 2 3 →