Wound Dressing: From Nanomaterials to Diagnostic Dressings and Healing Evaluations

被引：362

作者：

Zeng, Qiankun ^{[1
,2
]}

Qi, Xiaoliang ^{[5
]}

Shi, Guoyue ^{[1
,2
]}

Zhang, Min ^{[1
,2
]}

Haick, Hossam ^{[3
,4
]}

机构：

[1] East China Normal Univ, Sch Chem & Mol Engn, Shanghai 200241, Peoples R China

[2] East China Normal Univ, Shanghai Key Lab Urban Ecol Proc & Ecorestorat, Shanghai Key Lab Multidimens Informat Proc & Engn, Res Ctr Nanophoton & Adv Instrument,Minist Educ, Shanghai 200241, Peoples R China

[3] Technion Israel Inst Technol, Dept Chem Engn, IL-320003 Haifa, Israel

[4] Xidian Univ, Sch Adv Mat & Nanotechnol, Interdisciplinary Res Ctr Smart Sensors, Xian 710126, Peoples R China

[5] Wenzhou Med Univ, State Key Lab Ophthalmol Optometry & Vis Sci, Sch Ophthalmol & Optometry, Sch Biomed Engn, Wenzhou 325027, Peoples R China

来源：

ACS NANO | 2022年 / 16卷 / 02期

基金：

中国国家自然科学基金;

关键词：

wound; dressing; nanomaterial; healing; sensor; diagnostics; monitoring; therapeutics; ANTIBACTERIAL ACTIVITY; PHOTODYNAMIC THERAPY; HYDROGEL; BACTERIA; CHITOSAN; NANOPARTICLES; ADHESIVES; CHEMISTRY; ARRAY;

D O I：

10.1021/acsnano.1c08411

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Wound dressings based on nanomaterials play a crucial role in wound treatment and are widely used in a whole range of medical settings, from minor to life-threatening tissue injuries. This article presents an educational review on the accumulating knowledge in this multidisciplinary area to lay out the challenges and opportunities that lie ahead and ignite the further and faster development of clinically valuable technologies. The review analyzes the functional advantages of nanomaterial-based gauzes and hydrogels as well as hybrid structures thereof. On this basis, the review presents state-of-the-art advances to transfer the (semi)blind approaches to the evaluation of a wound state to smart wound dressings that enable real-time monitoring and diagnostic functions that could help in wound evaluation during healing. This review explores the translation of nanomaterial-based wound dressings and related medical aspects into real-world use. The ongoing challenges and future opportunities associated with nanomaterial-based wound dressings and related clinical decisions are presented and reviewed.

引用

页码：1708 / 1733

页数：26

共 137 条

[1] A serotonin-modified hyaluronic acid hydrogel for multifunctional hemostatic adhesives inspired by a platelet coagulation mediator [J].