Ionic Liquid-Based Materials for Biomedical Applications

被引:65
作者
Correia, Daniela Maria [1 ,2 ]
Fernandes, Liliana Correia [1 ]
Fernandes, Margarida Macedo [1 ,3 ]
Hermenegildo, Bruno [4 ]
Meira, Rafaela Marques [1 ,3 ]
Ribeiro, Clarisse [1 ,3 ]
Ribeiro, Sylvie [1 ,5 ]
Reguera, Javier [4 ]
Lanceros-Mendez, Senentxu [1 ,6 ]
机构
[1] Univ Minho, Ctr Phys, P-4710058 Braga, Portugal
[2] Univ Tras Os Montes & Alto Douro, Ctr Chem, P-5000801 Vila Real, Portugal
[3] Univ Minho, CEB Ctr Biol Engn, P-4710057 Braga, Portugal
[4] Basque Ctr Mat Applicat & Nanostruct, BCMat, UPV EHU Sci Pk, Leioa 48940, Spain
[5] Univ Minho, IB S Inst Res & Innovat Biosustainabil, P-4710057 Braga, Portugal
[6] Basque Fdn Sci, Ikerbasque, Bilbao 48009, Spain
关键词
biomedical applications; ionic liquids; IL-polymer based materials; DEEP EUTECTIC SOLVENTS; BOVINE SERUM-ALBUMIN; ANTIMICROBIAL ACTIVITIES; 1-ETHYL-3-METHYLIMIDAZOLIUM ACETATE; ALKYLTRIBUTYLPHOSPHONIUM CHLORIDES; TOXICITY ASSESSMENT; MICELLE FORMATION; SELF-AGGREGATION; HYDROGEL BEADS; POTENTIAL TOOL;
D O I
10.3390/nano11092401
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Ionic liquids (ILs) have been extensively explored and implemented in different areas, ranging from sensors and actuators to the biomedical field. The increasing attention devoted to ILs centers on their unique properties and possible combination of different cations and anions, allowing the development of materials with specific functionalities and requirements for applications. Particularly for biomedical applications, ILs have been used for biomaterials preparation, improving dissolution and processability, and have been combined with natural and synthetic polymer matrixes to develop IL-polymer hybrid materials to be employed in different fields of the biomedical area. This review focus on recent advances concerning the role of ILs in the development of biomaterials and their combination with natural and synthetic polymers for different biomedical areas, including drug delivery, cancer therapy, tissue engineering, antimicrobial and antifungal agents, and biosensing.
引用
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页数:42
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