Chemoenzymatic approaches to lycorine-type Amaryllidaceae alkaloids:: Total syntheses of ent-lycoricidine, 3-epi-ent-lycoricidine, and 4-deoxy-3-epi-ent-lycoricidine

被引：64

作者：

Matveenko, Maria ^{[1
]}

Kokas, Okanya J. ^{[1
]}

Banwell, Martin G. ^{[1
]}

Willis, Anthony C. ^{[1
]}

机构：

[1] Australian Natl Univ, Res Sch Chem, Inst Adv Studies, Canberra, ACT 0200, Australia

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 18期

关键词：

D O I：

10.1021/ol701552r

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The readily available and enzymatically derived cis-1,2-dihydrocatechol 4 has been elaborated, over 11 steps including an Overman rearrangement, into the non-natural enantiomer, (-)-1, of the alkaloid lycoricidine [(+)-1]. Related chemistries have provided analogues 18, 19, and 26.

引用

页码：3683 / 3685

页数：3

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