Emergence of an extensively drug-resistant (XDR) Streptococcus pneumoniae serotype 15A by capsular switching

被引：5
|
作者：
Baek, Jin Yang [1 ,2 ]
Kim, So Hyun [1 ,2 ]
Kang, Cheol-In [2 ]
Chung, Doo Ryeon [1 ,2 ]
Peck, Kyong Ran [2 ]
Song, Jae-Hoon [1 ]
Ko, Kwan Soo [1 ,3 ,4 ]
机构：
[1] APFID, Seoul, South Korea
[2] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Div Infect Dis, Seoul, South Korea
[3] Sungkyunkwan Univ, Sch Med, Dept Mol Cell Biol, Suwon 16419, South Korea
[4] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Suwon, South Korea
来源：
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY | 2018年 / 308卷 / 08期
基金：
新加坡国家研究基金会;
关键词：
Extensively drug-resistant; Pneumococci; Serotype; 15A; 11A; ST8279; Capsular switching; PNEUMOCOCCAL CONJUGATE VACCINATION; NASOPHARYNGEAL CARRIAGE; UNITED-STATES; CHILDREN; PREVALENCE; INCREASE; KOREA; CLONE; ERA;
D O I：
10.1016/j.ijmm.2018.08.004
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Recently, we have identified an extensively drug-resistant (XDR) Streptococcus pneumoniae serotype 15A isolate from a patient with bacterial meningitis. It belonged to sequence type 8279 (ST8279), a clone identified as XDR serotype 11A isolated in South Korea. We obtained and compared the genome sequences of an XDR 15A and an XDR 11A isolate. The genomes of two XDR isolates were highly identical, except for the capsular polysaccharide (cps) locus and another small region. Capsular switching from 11A to 15A may have occurred via recombination of the cps locus. The emergence of a new XDR clone via capsular switching would be a great concern for public health and in clinical settings.
引用
收藏
页码：986 / 989
页数：4
相关论文
共 50 条
  • [21] Nosocomial outbreak of multi-resistant Streptococcus pneumoniae serotype 15A in a centre for chronic pulmonary diseases
    Guido J. H. Bastiaens
    Amelieke J. H. Cremers
    Jordy P. M. Coolen
    Mayke T. Nillesen
    Martin J. Boeree
    Joost Hopman
    Heiman F. L. Wertheim
    Antimicrobial Resistance & Infection Control, 7
  • [22] Can octapeptin antibiotics combat extensively drug-resistant (XDR) bacteria?
    Blaskovich, Mark A. T.
    Pitt, Miranda E.
    Elliott, Alysha G.
    Cooper, Matthew A.
    EXPERT REVIEW OF ANTI-INFECTIVE THERAPY, 2018, 16 (06) : 485 - 499
  • [23] Extensively drug-resistant tuberculosis (XDR TB): Air travel exposure
    不详
    INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2007, 11 (04) : 288 - 288
  • [24] Managing a Case of Extensively Drug-Resistant (XDR) Pulmonary Tuberculosis in Singapore
    Phua, Chee Kiang
    Chee, Cynthia B. E.
    Chua, Angeline P. G.
    Gan, Suay Hong
    Ahmed, Aneez D. B.
    Wang, Yee Tang
    ANNALS ACADEMY OF MEDICINE SINGAPORE, 2011, 40 (03) : 132 - 135
  • [25] Emergence of a novel conjugative hybrid virulence multidrug-resistant plasmid in extensively drug-resistant Klebsiella pneumoniae ST15
    Li, Ruichao
    Cheng, Jing
    Dong, Huiyue
    Li, Leyuan
    Liu, Wentian
    Zhang, Chunli
    Feng, Xianju
    Qin, Shangshang
    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2020, 55 (06)
  • [26] Extensively Drug-Resistant (XDR) Typhoid: Evolution, Prevention, and Its Management
    Akram, Javed
    Khan, Arsalan Shamim
    Khan, Hassan Ahmed
    Gilani, Syed Amir
    Akram, Shehla Javed
    Ahmad, Fridoon Jawad
    Mehboob, Riffat
    BIOMED RESEARCH INTERNATIONAL, 2020, 2020
  • [27] Extensively Drug-resistant Tuberculosis (XDR-TB)-inhibitors to Overcome the Scourge of Drug-resistant Tuberculosis: a Perspective
    Harun Patel
    Iqrar Ahmad
    Harsha Jadhav
    Rahul Pawara
    Anand Mundada
    Matin Shaikh
    Sanjay Surana
    Reviews and Advances in Chemistry, 2020, 10 (3-4): : 112 - 139
  • [28] Emergence of an extensively drug-resistant Neisseria gonorrhoeae clone
    van Hal, Sebastiaan J.
    Sherry, Norelle
    Coombs, Geoff
    Mowlaboccus, Shakeel
    Whiley, David M.
    Lahra, Monica M.
    LANCET INFECTIOUS DISEASES, 2024, 24 (09): : e547 - e548
  • [29] Emergence of Extensively Drug-Resistant Haemophilus parainfluenzae in Switzerland
    Tinguely, Regula
    Seiffert, Salome N.
    Furrer, Hansjakob
    Perreten, Vincent
    Droz, Sara
    Endimiani, Andrea
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2013, 57 (06) : 2867 - 2869
  • [30] The Genetic Structures of an Extensively Drug Resistant (XDR) Klebsiella pneumoniae and Its Plasmids
    Li, Ling
    Yu, Tao
    Ma, Yanan
    Yang, Zhongjun
    Wang, Wenjia
    Song, Xiaobo
    Shen, Yu
    Guo, Tingting
    Kong, Jian
    Wang, Mingyu
    Xu, Hai
    FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2019, 8
12345