Glucose Biosensor Using Glucose Oxidase and Electrospun Mn2O3-Ag Nanofibers

被引：38

作者：

Huang, Shan ^{[2
]}

Ding, Yu ^{[1
]}

Liu, Yixin ^{[1
]}

Su, Liang ^{[1
]}

Filosa, Raymond, Jr. ^{[1
]}

Lei, Yu ^{[1
]}

机构：

[1] Univ Connecticut, Dept Chem Mat & Biomol Engn, Storrs, CT 06269 USA

[2] Univ Connecticut, Biomed Engn Program, Storrs, CT 06269 USA

来源：

ELECTROANALYSIS | 2011年 / 23卷 / 08期

关键词：

Glucose; Nanofibers; Electrochemistry; Electrospinning; Glucose oxidase; GLASSY-CARBON ELECTRODE; DIRECT ELECTROCHEMISTRY; OXYGEN-ELECTRODE; BODY-TEMPERATURE; PASTE ELECTRODE; NANOTUBES; NANOPARTICLES; SENSOR; IMMOBILIZATION; COMPOSITE;

D O I：

10.1002/elan.201100221

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The highly porous Mn2O3-Ag nanofibers were fabricated by a facile two-step procedure (electrospinning and calcination). The structure and composition of the Mn2O3-Ag nanofibers were characterized by SEM, TEM, XRD, EDX and SAED. The as-prepared Mn2O3-Ag nanofibers were then employed as the immobilization matrix for glucose oxidase (GOD) to construct an amperometric glucose biosensor. The biosensor shows fast response to glucose, high sensitivity (40.60 mu A mM(-1) cm(-2)), low detection limit (1.73 mu M at S/N=3), low K-m.app value and excellent selectivity. These results indicate that the novel Mn2O3-Ag nanfibers-GOD composite has great potential application in oxygen-reduction based glucose biosensing.

引用

页码：1912 / 1920

页数：9

共 65 条

[1] A Single ZnO Nanofiber-Based Highly Sensitive Amperometric Glucose Biosensor [J].

Ahmad, Mashkoor ;

Pan, Caofeng ;

Luo, Zhixiang ;

Zhu, Jing .

JOURNAL OF PHYSICAL CHEMISTRY C, 2010, 114 (20) :9308-9313

[2] Glucose oxidase - An overview [J].

Bankar, Sandip B. ;

Bule, Mahesh V. ;

Singhal, Rekha S. ;

Ananthanarayan, Laxmi .

BIOTECHNOLOGY ADVANCES, 2009, 27 (04) :489-501

[3] New nanostructured TiO2 for direct electrochemistry and glucose sensor applications [J].

Bao, Shu-Juan ;

Li, Chang Ming ;

Zang, Jian-Feng ;

Cui, Xiao-Qiang ;

Qiao, Yan ;

Guo, Jun .

ADVANCED FUNCTIONAL MATERIALS, 2008, 18 (04) :591-599

[4]

Celej MS, 1998, ELECTROANAL, V10, P771, DOI 10.1002/(SICI)1521-4109(199809)10:11<771::AID-ELAN771>3.0.CO

[5]

2-P

[6] AMPEROMETRIC GLUCOSE BIOSENSOR BASED ON A TETRATHIAFULVALENE-MEDIATED EPOXY-GRAPHITE BIOCOMPOSITE [J].

CESPEDES, F ;

MARTINEZFABREGAS, E ;

ALEGRET, S .

ELECTROANALYSIS, 1994, 6 (09) :759-763

[7] Enhanced electrochemical oxygen reduction-based glucose sensing using glucose oxidase on nanodendritic poly[meso-tetrakis(2-thienyl)porphyrinato]cobalt(II)-SWNTs composite electrodes [J].

Chen, Wei ;

Ding, Yu ;

Akhigbe, Joshua ;

Brueckner, Christian ;

Li, Chang Ming ;

Lei, Yu .

BIOSENSORS & BIOELECTRONICS, 2010, 26 (02) :504-510

[8] Enzyme immobilization on Ag nanoparticles/polyaniline nanocomposites [J].

Crespilho, Frank N. ;

Iost, Rodrigo M. ;

Travain, Silmar A. ;

Oliveira, Osvaldo N., Jr. ;

Zucolotto, Valtencir .

BIOSENSORS & BIOELECTRONICS, 2009, 24 (10) :3073-3077

[9] Highly sensitive amperometric glucose biosensor based on glassy carbon electrode with copper/palladium coating [J].

Dai, YQ ;

Shiu, KK .

ELECTROANALYSIS, 2004, 16 (21) :1806-1813

[10] Direct electrochemistry of glucose oxidase and biosensing for glucose based on boron-doped carbon nanotubes modified electrode [J].

Deng, Chunyan ;

Chen, Jinhua ;

Chen, Xiaoli ;

Mao, Chunhui ;

Nie, Lihua ;

Yao, Shouzhuo .

BIOSENSORS & BIOELECTRONICS, 2008, 23 (08) :1272-1277

← 1 2 3 4 5 6 7 →