In vivo 1H NMR spectroscopy of individual human brain metabolites at moderate field strengths

被引:25
|
作者
Trabesinger, AH
Meier, D
Boesiger, P [1 ]
机构
[1] Swiss Fed Inst Technol, ETH, Inst Biomed Engn, Zurich, Switzerland
[2] Univ Zurich, CH-8006 Zurich, Switzerland
关键词
1H MRS; spectral editing; strong coupling; human brain;
D O I
10.1016/j.mri.2003.08.029
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
This article reviews spectral editing techniques for in vivo H-1 NMR spectroscopy of human brain tissue at moderate field strengths of 1.5-3 Tesla. Various aspects of H-1 NMR spectroscopy are discussed with regard to in vivo applications. The parameter set [delta, J, n] (delta being the relative chemical shift, J the scalar coupling constant and n the number of coupled spins) is used to characterize the spin systems under investigation and to classify the editing techniques that are used in in vivo H-1 NMR spectroscopy. (C) 2003 Elsevier Inc. All rights reserved.
引用
收藏
页码:1295 / 1302
页数:8
相关论文
共 50 条
  • [1] In vivo 1H NMR spectroscopy of the human brain at 7 T
    Tkác, I
    Andersen, P
    Adriany, G
    Merkle, H
    Ugurbil, K
    Gruetter, R
    MAGNETIC RESONANCE IN MEDICINE, 2001, 46 (03) : 451 - 456
  • [2] In vivo 1H NMR spectroscopy of the human brain at 9.4 T: Initial results
    Deelchand, Dinesh Kumar
    Van de Moortele, Pierre-Francois
    Adriany, Gregor
    Iltis, Isabelle
    Andersen, Peter
    Strupp, John P.
    Vaughan, J. Thomas
    Ugurbil, Kamil
    Henry, Pierre-Gilles
    JOURNAL OF MAGNETIC RESONANCE, 2010, 206 (01) : 74 - 80
  • [3] Human brain metabolism studied by 1H NMR spectroscopy
    Mangia, S.
    Giove, F.
    Nuzzo, M. D.
    Michaeli, S.
    Carruthers, A.
    Simpson, I.
    JOURNAL OF NEUROCHEMISTRY, 2009, 109 : 267 - 268
  • [4] 1H NMR detection of vitamin C in human brain in vivo
    Terpstra, M
    Gruetter, R
    MAGNETIC RESONANCE IN MEDICINE, 2004, 51 (02) : 225 - 229
  • [5] In vivo 1H NMR spectroscopy of rat brain at 1 ms echo time
    Tkác, I
    Starcuk, Z
    Choi, IY
    Gruetter, R
    MAGNETIC RESONANCE IN MEDICINE, 1999, 41 (04) : 649 - 656
  • [7] Quantitative 1H NMR spectroscopy of blood plasma metabolites
    de Graaf, RA
    Behar, KL
    ANALYTICAL CHEMISTRY, 2003, 75 (09) : 2100 - 2104
  • [8] Highly resolved in vivo 1H NMR spectroscopy of the mouse brain at 9.4 T
    Tkác, I
    Henry, PG
    Andersen, P
    Keene, CD
    Low, WC
    Gruetter, R
    MAGNETIC RESONANCE IN MEDICINE, 2004, 52 (03) : 478 - 484
  • [9] Rat strain-dependent variations in brain metabolites detected by in vivo 1H NMR spectroscopy at 16.4T
    Hong, Sung-Tak
    Balla, David Z.
    Choi, Changho
    Pohmann, Rolf
    NMR IN BIOMEDICINE, 2011, 24 (10) : 1401 - 1407
  • [10] The neurochemical profile quantified by in vivo 1H NMR spectroscopy
    Duarte, Joao M. N.
    Lei, Hongxia
    Mlynarik, Vladimir
    Gruetter, Rolf
    NEUROIMAGE, 2012, 61 (02) : 342 - 362