Ethanol Lock Therapy for the Treatment of Intravenous Catheter Infections That Have Failed Standard Treatment

被引：21

作者：

Blackwood, Roland Alexander ^{[1
]}

Issa, Mohamad ^{[1
]}

Klein, Kristin ^{[1
]}

Mody, Rajen ^{[1
]}

Willers, Michelle ^{[1
]}

Teitelbaum, Daniel ^{[1
]}

机构：

[1] Univ Michigan, 1500 East Med Ctr Dr,D5101 Med Profess Bldg, Ann Arbor, MI 48109 USA

来源：

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY | 2017年 / 6卷 / 01期

关键词：

catheter infections; ethanol locks; fungal infections; BLOOD-STREAM INFECTIONS; INTRAVASCULAR DEVICES; PEDIATRIC-PATIENTS; PREVENTION;

D O I：

10.1093/jpids/piv060

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

This study used ethanol lock therapy (ELT) to treat intravenous catheter infections that had failed standard intravenous antimicrobial treatment. Of 15 patients enrolled, 13 were successfully treated with ELT. Twenty-one organisms were identified: 12 bacteria, 9 fungi. Eight of the 9 fungi were eradicated, and no patient became hemodynamically unstable on treatment.

引用

页码：94 / 97

页数：4

共 50 条

[41] Generalized and Prolonged Use of Gentamicin-Lock Therapy Reduces Hemodialysis Catheter-Related Infections Due to Gram Negatives
Padilla-Orozco, Magaly
Mendoza-Flores, Lidia
Herrera-Alonso, Alicia
Garza Gonzalez, Elvira
Gutierrez Ferman, Jessica Lizeth
Manuel Rodriguez-Lopez, Juan
Bocanegra-Ibarias, Paola
Camacho-Ortiz, Adrian
NEPHRON, 2019, 143 (02) : 86 - 91
[42] Central venous catheter-associated bloodstream infections in pediatric hematology-oncology patients and effectiveness of antimicrobial lock therapy
Tsai, Hsing-Chen
Huang, Li-Min
Chang, Luan-Yin
Lee, Ping-Ing
Chen, Jong-Ming
Shao, Pei-Lan
Hsueh, Po-Ren
Sheng, Wang-Huei
Chang, Yu-Ching
Lu, Chun-Yi
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION, 2015, 48 (06) : 639 - 646
[43] Peritoneal catheter exit-site infections: Predisposing factors, prevention and treatment
Thodis, E
Passadakis, P
Ossareh, S
Panagoutsos, S
Vargemezis, V
Oreopoulos, DG
INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, 2003, 26 (08) : 698 - 714
[44] Successful Salvage of Central Venous Catheters in Patients with Catheter-Related or Central Line-Associated Bloodstream Infections by Using a Catheter Lock Solution Consisting of Minocycline, EDTA, and 25% Ethanol
Raad, Issam
Chaftari, Anne-Marie
Zakhour, Ramia
Jordan, Mary
Al Hamal, Zanaib
Jiang, Ying
Yousif, Ammar
Garoge, Kumait
Mulanovich, Victor
Viola, George M.
Kanj, Soha
Pravinkumar, Egbert
Rosenblatt, Joel
Hachem, Ray
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2016, 60 (06) : 3426 - 3432
[45] Hyperbaric oxygen therapy as an adjuvant to standard therapy in the treatment of diabetic foot ulcers
Kumar, Atit
Shukla, Usha
Prabhakar, Tallamraju
Srivastava, Dhiraj
JOURNAL OF ANAESTHESIOLOGY CLINICAL PHARMACOLOGY, 2020, 36 (02) : 213 - 218
[46] A randomised controlled trial of Heparin versus EthAnol Lock THerapY for the prevention of Catheter Associated infecTion in Haemodialysis patients - the HEALTHY-CATH trial
Broom, Jennifer K.
Krishnasamy, Rathika
Hawley, Carmel M.
Playford, E. Geoffrey
Johnson, David W.
BMC NEPHROLOGY, 2012, 13
[47] Antibiotic lock therapy for the treatment of peripherally inserted central venous catheter-related bloodstream infection in patients with hematological malignancies: a single center retrospective study
Zhang, Qin
Huo, Yujia
Li, Chengfei
Sun, Qinggang
Xi, Xi
Sun, Rui
Sun, Qingju
Jiang, Meijuan
Li, Guang
ANNALS OF HEMATOLOGY, 2025, : 1975 - 1984
[48] Combination Therapy for Treatment of Infections with Gram-Negative Bacteria
Tamma, Pranita D.
Cosgrove, Sara E.
Maragakis, Lisa L.
CLINICAL MICROBIOLOGY REVIEWS, 2012, 25 (03) : 450 - 470
[49] Comparing ethanol lock therapy versus vancomycin lock in a salvation strategy for totally implantable vascular access device infections due to coagulase-negative staphylococci (the ETHALOCK study): a prospective double-blind randomized clinical trial
Lesens, Olivier
Forestier, Emmanuel
Botelho-Nevers, Elisabeth
Pavese, Patricia
David, Gary
Nougarede, Bertrand
Corbin, Violaine
Pereira, Bruno
Aumeran, Claire
Sauvat, Leo
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2024, 43 (02) : 223 - 232
[50] Treatment and secondary prophylaxis with ethanol lock therapy for central line-associated bloodstream infection in paediatric cancer: a randomised, double-blind, controlled trial
Wolf, Joshua
Connell, Tom G.
Allison, Kim J.
Tang, Li
Richardson, Julie
Branum, Kristen
Borello, Eloise
Rubnitz, Jeffrey E.
Gaur, Aditya H.
Hakim, Hana
Su, Yin
Federico, Sara M.
Mechinaud, Francoise
Hayden, Randall T.
Monagle, Paul
Worth, Leon J.
Curtis, Nigel
Flynn, Patricia M.
LANCET INFECTIOUS DISEASES, 2018, 18 (08) : 854 - 863

← 1 2 3 4 5 →