Ethanol Lock Therapy for the Treatment of Intravenous Catheter Infections That Have Failed Standard Treatment

被引:21
|
作者
Blackwood, Roland Alexander [1 ]
Issa, Mohamad [1 ]
Klein, Kristin [1 ]
Mody, Rajen [1 ]
Willers, Michelle [1 ]
Teitelbaum, Daniel [1 ]
机构
[1] Univ Michigan, 1500 East Med Ctr Dr,D5101 Med Profess Bldg, Ann Arbor, MI 48109 USA
关键词
catheter infections; ethanol locks; fungal infections; BLOOD-STREAM INFECTIONS; INTRAVASCULAR DEVICES; PEDIATRIC-PATIENTS; PREVENTION;
D O I
10.1093/jpids/piv060
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
This study used ethanol lock therapy (ELT) to treat intravenous catheter infections that had failed standard intravenous antimicrobial treatment. Of 15 patients enrolled, 13 were successfully treated with ELT. Twenty-one organisms were identified: 12 bacteria, 9 fungi. Eight of the 9 fungi were eradicated, and no patient became hemodynamically unstable on treatment.
引用
收藏
页码:94 / 97
页数:4
相关论文
共 50 条
  • [21] Preemptive Ethanol Lock Therapy in Pediatric Hematology/Oncology Patients With Catheter-Associated Bloodstream Infection: Impact on Length of Stay, Cost, and Catheter Salvage
    McGrath, Eric
    Du, Wei
    Rajpurkar, Madhvi
    CLINICAL PEDIATRICS, 2018, 57 (03) : 285 - 293
  • [22] In vitro activities of N-acetyl cysteine and levofloxacin as a catheter lock therapy against catheter-associated infections
    Mansouri, M. David
    Ramanthan, Venkat
    Mansouri, Dena L.
    Hull, Richard A.
    JOURNAL OF APPLIED MICROBIOLOGY, 2022, 132 (05) : 3915 - 3924
  • [23] Daptomycin Antibiotic Lock Therapy in a Rat Model of Staphylococcal Central Venous Catheter Biofilm Infections
    Van Praagh, Andrew D. G.
    Li, Tongchuan
    Zhang, Shuxin
    Arya, Anu
    Chen, Liping
    Zhang, Xi-Xian
    Bertolami, Shellie
    Mortin, Lawrence I.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2011, 55 (09) : 4081 - 4089
  • [24] Prevention and Treatment of Urinary Catheter-Associated Infections
    Al Mohajer, Mayar
    Darouiche, Rabih O.
    CURRENT INFECTIOUS DISEASE REPORTS, 2013, 15 (02) : 116 - 123
  • [25] Prevention and Treatment of Urinary Catheter-Associated Infections
    Mayar Al Mohajer
    Rabih O. Darouiche
    Current Infectious Disease Reports, 2013, 15 : 116 - 123
  • [26] Hydrochloric Acid Treatment of Tunneled Central Venous Catheter Infections in Children With Cancer
    Larsen, Line Nordahl
    Malchau, Emma
    Kristensen, Brian
    Schroeder, Henrik
    JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2011, 33 (02) : E64 - E68
  • [27] Antifungal therapy for the treatment of CNS infections
    Aboabdo, Moeen
    Mishkin, Aaron
    CURRENT FUNGAL INFECTION REPORTS, 2024, 18 (02) : 146 - 153
  • [28] Significant Reduction in Central Venous Catheter-related Bloodstream Infections in Children on HPN After Starting Treatment With Taurolidine Line Lock
    Chu, Hui-Ping
    Brind, Joanne
    Tomar, Rajeev
    Hill, Susan
    JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2012, 55 (04) : 403 - 407
  • [29] Efficacy of ethanol locks to reduce the incidence of catheter-related bloodstream infections for home parenteral nutrition pediatric patients: comparison of therapeutic treatment with prophylactic treatment
    Takafumi Kawano
    Tatsuru Kaji
    Shun Onishi
    Koji Yamada
    Waka Yamada
    Kazuhiko Nakame
    Motoi Mukai
    Satoshi Ieiri
    Pediatric Surgery International, 2016, 32 : 863 - 867
  • [30] Adjunctive management of central line-associated bloodstream infections with 70% ethanol-lock therapy
    Kubiak, David W.
    Gilmore, Erin T.
    Buckley, Mary W.
    Lynch, Robert
    Marty, Francisco M.
    Koo, Sophia
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2014, 69 (06) : 1665 - 1668