PHARMACOGNOSTIC EVALUATION OF TURMERIC (CURCUMA LONGA) EXTRACTS IN DIABETIC WOUND HEALING

被引：0

作者：

Khan, M. A. ^{[1
]}

Shahzadi, T. ^{[1
]}

Malik, S. A. ^{[2
,4
]}

Shahid, M. ^{[1
]}

Ismail, M. ^{[1
]}

Zubair, M. ^{[1
]}

Iqbal, S. ^{[3
]}

机构：

[1] Govt Coll Univ, Dept Bioinformat & Biotechnol, Faisalabad 38000, Pakistan

[2] Univ Sargodha, Dept Biochem, Sargodha Med Coll, Sargodha 40100, Pakistan

[3] Univ Vet & Anim Sci, Dept Food Sci & Human Nutr, Lahore, Pakistan

[4] Emory Univ, Div Digest Dis, Dept Med, Sch Med, Atlanta, GA 30322 USA

来源：

JOURNAL OF ANIMAL AND PLANT SCIENCES | 2019年 / 29卷 / 01期

关键词：

Curcuma longa; Pharmacology; Diabetes mellitus; Mice; Glucose Tolerance Test; MODEL;

D O I：

暂无

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Diabetic wound management has always been a challenge for health care providers and biomedical researchers. The present study was designed to investigate the wound healing potential of South Asian spice turmeric, which is rich in polyphenols, and honey in Alloxan-induced diabetic mouse model. Wound healing was improved significantly in topically applied turmeric, honey and insulin (as positive control) when compared with diabetic non-treated control, however highest wound healing was observed in the case of turmeric. Similarly, diabetic mice on oral turmeric showed improved healing as compared to the diabetic controls. Moreover, diabetic mice on oral turmeric showed enhanced glucose tolerance test. On the basis of above results we surmise that turmeric improves the healing activity in diabetic wounds by enhancing the glucose sensitivity. Our data emphasize the idea of using turmeric as ethnomedicine for diabetic wound healing.

引用

页码：68 / 74

页数：7

共 29 条

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