Nanochemoprevention by encapsulation of (-)-epigallocatechin-3-gallate with bioactive peptides/chitosan nanoparticles for enhancement of its bioavailability

被引:108
作者
Hu, Bing [1 ,2 ]
Ting, Yuwen [2 ]
Yang, Xiaoqing [2 ]
Tang, Wenping [2 ]
Zeng, Xiaoxiong [1 ]
Huang, Qingrong [2 ]
机构
[1] Nanjing Agr Univ, Coll Food Sci & Technol, Nanjing 210095, Jiangsu, Peoples R China
[2] Rutgers State Univ, Dept Food Sci, New Brunswick, NJ 08901 USA
基金
美国农业部;
关键词
POORLY ABSORBABLE DRUGS; GREEN TEA CATECHINS; ABSORPTION ENHANCERS; CANCER PREVENTION; MOLECULAR-WEIGHT; DELIVERY-SYSTEMS; CACO-2; CELLS; CHITOSAN; TRANSPORT; EXTRACTION;
D O I
10.1039/c2cc17295j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Nanochemoprevention by oral consumption was developed by the encapsulation of (-)-epigallocatechin-3-gallate (EGCG) with nanoparticles that were electrostatically assembled from bioactive caseinophosphopeptides and chitosan, which was highly biocompatible and able to enhance the bioavailability of EGCG.
引用
收藏
页码:2421 / 2423
页数:3
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