Betaine excretion correlates with plasma homocysteine when plasma lipids are elevated

被引:6
作者
Lever, Michael [1 ,2 ]
Slow, Sandy [1 ]
George, Peter M. [1 ,2 ]
Chambers, Stephen T. [2 ]
机构
[1] Canterbury Hlth Labs, Clin Biochem Unit, Canterbury, New Zealand
[2] Christchurch Sch Med & Hlth Sci, Dept Pathol, Christchurch, New Zealand
关键词
Betaine; Homocysteine; Non-HDL cholesterol; Metabolic syndrome; GLYCINE BETAINE; CHOLINE;
D O I
10.1016/j.clinbiochem.2011.10.021
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Objectives: To reconcile observing a positive correlation of betaine excretion with homocysteine in lipid disorder patients but not other study groups. Design and methods: Correlations were estimated in subgroups of a control group and the lipid disorder patients. Results: Plasma non high-density lipoprotein (non-HDL) cholesterol differed (p<0.0001) between the groups. The correlation increased with the median plasma non-HDL cholesterol in subgroups. Conclusions: This correlation is associated with patients with elevated plasma lipids. (C) 2011 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:154 / 156
页数:3
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