Annihilation Upconversion in Cells by Embedding the Dye System in Polymeric Nanocapsules

被引：98
作者：
Wohnhaas, Christian [1 ]
Turshatov, Andrey [1 ]
Mailaender, Volker [1 ,2 ]
Lorenz, Steffen [1 ]
Baluschev, Stanislav [1 ,3 ]
Miteva, Tzenka [4 ]
Landfester, Katharina [1 ]
机构：
[1] Max Planck Inst Polymer Res, D-55128 Mainz, Germany
[2] Univ Med Johannes Gutenberg Univ, Dept Med 3, D-55131 Mainz, Germany
[3] Sofia Univ St Kliment Ochridski, Opt & Spect Dept, Fac Phys, Sofia 1164, Bulgaria
[4] Sony Deutschland GmbH, Mat Sci Lab, D-70327 Stuttgart, Germany
来源：
MACROMOLECULAR BIOSCIENCE | 2011年 / 11卷 / 06期
关键词：
annihilation upconversion; metallated macrocycles; miniemulsion polymerization; nanocapsules; TRIPLET-TRIPLET ANNIHILATION; NANOPARTICLES; ENHANCEMENT; ABSORPTION; EXCITATION; IONS;
D O I：
10.1002/mabi.201000451
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The first energetically conjoined TTA-assisted photon energy upconversion operating in cell tissue is described. The synthesized nanocapsules with the encapsulated UC dye system consisting of an emitter and a sensitizer show very efficient UC emission in aqueous dispersion under extremely low excitation intensity down to 0.05W.cm(-2) so that tissue and cells are not affected by the excitation light. The demonstrated sub-linear intensity dependence of the UC emission is of crucial importance for life-science applications as the UC photon could serve as a local or in situ optical excitation source for subsequent light-triggered processes.
引用
收藏
页码：772 / 778
页数：7
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