Effects of beetroot juice supplementation on microvascular blood flow in older overweight and obese subjects: a pilot randomised controlled study

被引:25
作者
Ashor, A. W. [1 ,2 ]
Jajja, A. [1 ]
Sutyarjoko, A. [1 ]
Brandt, K. [3 ]
Qadir, O. [3 ]
Lara, J. [1 ]
Siervo, M. [1 ]
机构
[1] Newcastle Univ, Human Nutr Res Ctr, Inst Cellular Med, Newcastle Upon Tyne, England
[2] Univ Al Mustansiriyah, Dept Pharmacol, Coll Med, Baghdad, Iraq
[3] Newcastle Univ, Human Nutr Res Ctr, Sch Agr Food & Rural Dev, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England
关键词
DIETARY NITRATE; INORGANIC NITRATE; PRESSURE; NITRITE; DISEASE;
D O I
10.1038/jhh.2014.114
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Twenty-one older, overweight participants were randomised to 3 weeks of either beetroot juice concentrate or blackcurrant juice supplementation to test the effects on cutaneous microvascular reactivity during post-occlusive reactive hyperaemia (PORH). The study also tested whether the effects were maintained after 1 week from interrupting the supplementation. The peak hyperaemic blood flow and the PORH index were not different between the two interventions at the end of both supplementation and post-supplementation phases.
引用
收藏
页码:511 / 513
页数:3
相关论文
共 11 条
[1]  
D'Haene K, 2013, METHOD USING GAS CHR
[2]   Nitric oxide and oxidative stress in vascular disease [J].
Foerstermann, Ulrich .
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2010, 459 (06) :923-939
[3]   Effect of dietary nitrate on blood pressure, endothelial function, and insulin sensitivity in type 2 diabetes [J].
Gilchrist, Mark ;
Winyard, Paul G. ;
Aizawa, Kunihiko ;
Anning, Christine ;
Shore, Angela ;
Benjamin, Nigel .
FREE RADICAL BIOLOGY AND MEDICINE, 2013, 60 :89-97
[4]   Blood pressure-lowering effects of beetroot juice and novel beetroot-enriched bread products in normotensive male subjects [J].
Hobbs, Ditte A. ;
Kaffa, Nedi ;
George, Trevor W. ;
Methven, Lisa ;
Lovegrove, Julie A. .
BRITISH JOURNAL OF NUTRITION, 2012, 108 (11) :2066-2074
[5]   Inorganic Nitrate Supplementation Lowers Blood Pressure in Humans Role for Nitrite-Derived NO [J].
Kapil, Vikas ;
Milsom, Alexandra B. ;
Okorie, Michael ;
Maleki-Toyserkani, Sheiva ;
Akram, Farihah ;
Rehman, Farkhanda ;
Arghandawi, Shah ;
Pearl, Vanessa ;
Benjamin, Nigel ;
Loukogeorgakis, Stavros ;
MacAllister, Raymond ;
Hobbs, Adrian J. ;
Webb, Andrew J. ;
Ahluwalia, Amrita .
HYPERTENSION, 2010, 56 (02) :274-U174
[6]   Roles of dietary inorganic nitrate in cardiovascular health and disease [J].
Lundberg, Jon O. ;
Carlstrom, Mattias ;
Larsen, Filip J. ;
Weitzberg, Eddie .
CARDIOVASCULAR RESEARCH, 2011, 89 (03) :525-532
[7]   Inorganic nitrate: a major player in the cardiovascular health benefits of vegetables? [J].
Machha, Ajay ;
Schechter, Alan N. .
NUTRITION REVIEWS, 2012, 70 (06) :367-372
[8]   Dietary Nitrate Reverses Vascular Dysfunction in Older Adults With Moderately Increased Cardiovascular Risk [J].
Rammos, Christos ;
Hendgen-Cotta, Ulrike B. ;
Sobierajski, Julia ;
Bernard, Andrea ;
Kelm, Malte ;
Rassaf, Tienush .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2014, 63 (15) :1584-1585
[9]   Simultaneous Measurement of [15N]Nitrate and [15N]Nitrite Enrichment and Concentration in Urine by Gas Chromatography Mass Spectrometry as Pentafluorobenzyl Derivatives [J].
Tsikas, Dimitrios ;
Schwarz, Alexandra ;
Stichtenoth, Dirk O. .
ANALYTICAL CHEMISTRY, 2010, 82 (06) :2585-2587
[10]   Acute and chronic effects of dietary nitrate supplementation on blood pressure and the physiological responses to moderate-intensity and incremental exercise [J].
Vanhatalo, Anni ;
Bailey, Stephen J. ;
Blackwell, Jamie R. ;
DiMenna, Fred J. ;
Pavey, Toby G. ;
Wilkerson, Daryl P. ;
Benjamin, Nigel ;
Winyard, Paul G. ;
Jones, Andrew M. .
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2010, 299 (04) :R1121-R1131