Too Stiff, Too Late . . . Timing Is Everything in Antiangiogenic Treatment of Liver Fibrosis

被引：5

作者：

Greuter, Thomas ^{[1
]}

Shah, Vijay H. ^{[1
]}

机构：

[1] Mayo Clin, Rochester, MN 55905 USA

来源：

HEPATOLOGY | 2019年 / 69卷 / 01期

基金：

美国国家卫生研究院; 瑞士国家科学基金会;

关键词：

EXTRACELLULAR-MATRIX; MECHANOTRANSDUCTION; ANGIOGENESIS;

D O I：

10.1002/hep.30124

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

引用

页码：449 / 451

页数：3

共 8 条

[1] The role of extracellular matrix in retinal vascular development and preretinal neovascularization [J].

Bishop, Paul N. .

EXPERIMENTAL EYE RESEARCH, 2015, 133 :30-36

[2] Mechanotransduction and fibrosis [J].

Duscher, Dominik ;

Maan, Zeshaan N. ;

Wong, Victor W. ;

Rennert, Robert C. ;

Januszyk, Michael ;

Rodrigues, Melanie ;

Hu, Michael ;

Whitmore, Arnetha J. ;

Whittam, Alexander J. ;

Longaker, Michael T. ;

Gurtner, Geoffrey C. .

JOURNAL OF BIOMECHANICS, 2014, 47 (09) :1997-2005

[3] Mechanotransduction and extracellular matrix homeostasis [J].

Humphrey, Jay D. ;

Dufresne, Eric R. ;

Schwartz, Martin A. .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2014, 15 (12) :802-812

[4] ISOMETRIC CONTRACTION BY FIBROBLASTS AND ENDOTHELIAL-CELLS IN TISSUE-CULTURE - A QUANTITATIVE STUDY [J].

KOLODNEY, MS ;

WYSOLMERSKI, RB .

JOURNAL OF CELL BIOLOGY, 1992, 117 (01) :73-82

[5]

Korff T, 1999, J CELL SCI, V112, P3249

[6] Limited therapeutic efficacy of pioglitazone on progression of hepatic fibrosis in rats [J].

Leclercq, I. A. ;

Sempoux, C. ;

Starkel, P. ;

Horsmans, Y. .

GUT, 2006, 55 (07) :1020-1029

[7]

Liu LW, 2017, NAT MATER, V16, P1252, DOI [10.1038/NMAT5024, 10.1038/nmat5024]

[8] Intrahepatic angiogenesis and sinusoidal remodeling in chronic liver disease: New targets for the treatment of portal hypertension? [J].

Thabut, Dominique ;

Shah, Vijay .

JOURNAL OF HEPATOLOGY, 2010, 53 (05) :976-980

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