Vancomycin Induced Thrombocytopenia - Protracted Course in a Hemodialysis Patient

被引：7
作者：
Ajit, Nisha Elizabeth [1 ]
Devarashetty, Sindhu Priya [2 ]
Master, Samip [1 ]
机构：
[1] Ochsner Louisiana State Univ Hlth Sci, Hematol Oncol Dept, Shreveport, LA 71103 USA
[2] Ochsner Louisiana State Univ Hlth Sci, Dept Internal Med, Shreveport, LA 71103 USA
来源：
CASE REPORTS IN ONCOLOGY | 2019年 / 12卷 / 03期
关键词：
Vancomycin; Drug induced thrombocytopenia; End stage renal disease; IMMUNE THROMBOCYTOPENIA;
D O I：
10.1159/000503418
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Vancomycin induced thrombocytopenia (VIT) is an uncommon side effect of vancomycin which can manifest from mild petechiae to life-threatening bleed. Decreased renal clearance of vancomycin results in prolonged thrombocytopenia by antibody-mediated platelet destruction in the presence of vancomycin. Improvement in thrombocytopenia is achieved with the elimination of vancomycin. We describe a patient with end stage renal disease who experienced a protracted course of thrombocytopenia from vancomycin. We illustrate the mechanism of thrombocytopenia and the treatment modalities used by us and those described in literature. VIT is an important differential in patients with thrombocytopenia admitted to the hospital.
引用
收藏
页码：749 / 754
页数：6
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