The Importance of Surgical Margins in Melanoma

被引:38
作者
Ethun, Cecilia G. [1 ]
Delman, Keith A. [1 ]
机构
[1] Emory Univ, Winship Canc Inst, Dept Surg, Div Surg Oncol, 1365C Clifton Rd,NE Bldg C,2nd Floor, Atlanta, GA 30322 USA
关键词
prospective trial; guidelines; wide local excision; Mohs micrographic surgery; immunotherapy; MOHS MICROGRAPHIC SURGERY; LENTIGO-MALIGNA MELANOMA; TOPICAL 5-PERCENT IMIQUIMOD; ADJUVANT RADIATION-THERAPY; PRIMARY CUTANEOUS MELANOMA; NODE FIELD RELAPSE; STAGE-I MELANOMA; EXCISION MARGINS; NECK MELANOMA; PROGNOSTIC-FACTORS;
D O I
10.1002/jso.24111
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Optimization of margins to minimize morbidity and maximize local control is critical to the success of surgical management of primary melanomas. This article synthesizes the historical perspectives and key clinical trials that have contributed to the evolution of resection margins for melanoma, focusing on the importance of surgical margins in the context of an era of improvements in systemic therapy and greater use of minimally invasive techniques. (c) 2015 Wiley Periodicals, Inc.
引用
收藏
页码:339 / 345
页数:7
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