Cavin-2/SDPR in Cardiac Fibroblasts Modulates TGF-[beta]/Smad Signaling and Promotes Pressure Overload-induced Fibrosis

被引:0
|
作者
Higuchi, Yusuke [1 ]
Ogata, Takehiro [2 ]
Nakanishi, Naohiko [1 ]
Nishi, Masahiro [1 ]
Sakamoto, Akira [1 ]
Tsuji, Yumika [3 ]
Matoba, Satoaki [1 ]
机构
[1] Kyoto Prefectural Univ Med, Grad Sch Med Sci, Dept Cardiovasc Med, Kyoto, Japan
[2] Kyoto Prefectural Univ Med, Dept Pathol & Cell Regulat, Kyoto, Japan
[3] Kyoto Prefectural Univ Medicined, Grad Sch Med Sci, Dept Cardiovasc Med, Kyoto, Japan
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
520
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Simvastatin Inhibits TGF-[beta]1-induced Proliferation and Activation of Cardiac Fibroblasts Through Inhibition of SMAD Pathway
    Rizvi, Farhan
    Siddiqui, Ramail
    DeFranco, Alesandra
    Jayaprakash, Akhil
    Mirza, Mahek
    Emelyanova, Larisa
    Ross, Gracious
    Hulmohamedov, Ekhson
    O'Hair, Daniel
    Tajik, A. Jamil
    Jahangir, Arshad
    CIRCULATION RESEARCH, 2014, 115
  • [32] GSK-3α in Fibroblasts Attenuates Cardiac Fibrosis and Dysfunction Induced by Pressure Overload Through Modulation of TGFβ1
    Zhai, Peiyong
    Shirakabe, Akihiro
    Magrys, Bonaventure
    Sadoshima, Junichi
    CIRCULATION, 2015, 132
  • [33] USP7 Promotes TGF-β1 Signaling by De-Ubiquitinating Smad2/Smad3 in Pulmonary Fibrosis
    Tang, Fang
    Gong, Hongyan
    Ke, Tiantian
    Yang, Wenming
    Yang, Yuxuan
    Liu, Zhiyi
    DISCOVERY MEDICINE, 2024, 36 (187) : 1616 - 1626
  • [34] Cardiac Secreted Beta-2 Microglobulin Promotes Fibrosis Involving Epidermal Growth Factor Receptor Signaling During Pressure Overload
    Li, Yang
    Gong, Hui
    CIRCULATION, 2017, 136
  • [35] Velvet antler peptide prevents pressure overload-induced cardiac fibrosis via transforming growth factor (TGF)-β1 pathway inhibition
    Zhao, Lihong
    Mi, Yang
    Guan, Hongya
    Xu, Yan
    Mei, Yingwu
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2016, 783 : 33 - 46
  • [36] Loss of Endogenous HMGB2 Promotes Cardiac Dysfunction and Pressure Overload-Induced Heart Failure in Mice
    Sato, Michio
    Miyata, Keishi
    Tian, Zhe
    Kadomatsu, Tsuyoshi
    Ujihara, Yoshihiro
    Morinaga, Jun
    Horiguchi, Haruki
    Endo, Motoyoshi
    Zhao, Jiabin
    Zhu, Shunshun
    Sugizaki, Taichi
    Igata, Kimihiro
    Muramatsu, Masashi
    Minami, Takashi
    Ito, Takashi
    Bianchi, Marco E.
    Mohri, Satoshi
    Araki, Kimi
    Node, Koichi
    Oike, Yuichi
    CIRCULATION JOURNAL, 2019, 83 (02) : 368 - +
  • [37] Up-regulation of the kinin B2 receptor pathway modulates the TGF-β/Smad signaling cascade to reduce renal fibrosis induced by albumin
    Cardenas, Areli
    Campos, Javiera
    Ehrenfeld, Pamela
    Mezzano, Sergio
    Ruiz-Ortega, Marta
    Figueroa, Carlos D.
    Ardiles, Leopoldo
    PEPTIDES, 2015, 73 : 7 - 19
  • [38] Role of Leukotriene Receptor Antagonist on TGF-β and Smad2 Signaling in Bleomycin Induced Pulmonary Fibrosis.
    Lee, W. Y.
    Lee, B. G.
    Kim, S. T.
    Kim, C. J.
    Seo, H. S.
    Park, H. S.
    Park, J. Y.
    Kim, S. H.
    Yong, S. J.
    Shin, K. C.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2009, 179
  • [39] Activation of Kir2.1 improves myocardial fibrosis by inhibiting Ca2+ overload and the TGF-β1/Smad signaling pathway
    Rong, Yi
    Zhou, Xin
    Guo, Zhenli
    Zhang, Yingying
    Qin, Wenjuan
    Li, Li
    Si, Junqiang
    Yang, Rui
    Li, Xinzhi
    Ma, Ketao
    ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 55 (05) : 749 - 757
  • [40] Central neuregulin-1/ErbB signaling modulates cardiac function via sympathetic activity in pressure overload-induced heart failure
    Matsukawa, Ryuichi
    Hirooka, Yoshitaka
    Ito, Koji
    Honda, Nobuhiro
    Sunagawa, Kenji
    JOURNAL OF HYPERTENSION, 2014, 32 (04) : 817 - 825