Ischemic nephropathy - pathogenesis and treatment

被引：15

作者：

Adamczak, Marcin ^{[1
]}

Wiecek, Andrzej ^{[1
]}

机构：

[1] Med Univ Silesia, Dept Nephrol Endocrinol & Metab Dis, Katowice, Poland

来源：

NEFROLOGIA | 2012年 / 32卷 / 04期

关键词：

Ischemic nephropathy; Renal artery stenosis; Chronic kidney disease; Medical therapy; Renal angioplasty; RENAL-ARTERY STENOSIS; ATHEROSCLEROTIC RENOVASCULAR DISEASE; INCREASED OXIDATIVE STRESS; VASCULAR-DISEASE; UNITED-STATES; BLOOD-FLOW; HYPERTENSION; OXYGENATION; REVASCULARIZATION; PREVALENCE;

D O I：

10.3265/Nefrologia.pre2012.Apr.11472

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

In this review paper we would like to summarized the current knowledge concerning the pathogenesis and treatment of ischemic nephropathy. Epidemiological data suggest that the prevalence of ischemic nephropathy increases, especially among older individuals. The pathogenesis of this disease is more complex than just narrowing of the renal artery due to atherosclerosis. Renin-angiotension system, growth factors, different cytokines and chemokines may participate in the pathogenesis of ischemic nephropathy. Precise, clinically useful diagnostic criteria of the ischemic nephropathy have not been established, yet. Concerted medical management remains now the main therapeutic option for majority of patients with this disease and only in the selected patients revascularisation is nowadays indicated.

引用

页码：432 / 438

页数：7

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