THYROTOXIC PERIODIC PARALYSIS AND CHOREA: TWO UNCOMMON NEUROMUSCULAR COMPLICATIONS AS PRESENTING SYMPTOMS IN AN ADOLESCENT WITH NEWLY DIAGNOSED GRAVES' DISEASE: A CASE REPORT

被引:0
作者
Nakavachara, Pairunyar [1 ]
Suppakrucha, Montira [1 ]
Patjamontri, Supitcha [1 ]
Likasitwattanakul, Surachai [2 ]
机构
[1] Mahidol Univ, Siriraj Hosp, Fac Med, Div Pediat Endocrinol, Bangkok, Thailand
[2] Mahidol Univ, Siriraj Hosp, Fac Med, Div Pediat Neurol,Dept Pediat, 2 Wanglang Rd, Bangkok 10700, Thailand
关键词
Graves' disease; periodic paralysis; chorea; adolescent; HYPERTHYROID-INDUCED CHOREA; ASSOCIATION;
D O I
暂无
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Thyrotoxic periodic paralysis (TPP) and chorea are uncommon neurological complications of hyperthyroidism. Here, we report and describe a case of 14-year-old boy who presented with both TPP and chorea at his initial presentation with signs and symptoms of Graves' disease. After diagnosis, a combination of methimazole (MMI) and propranolol were started to control hyperthyroidism. TPP resolved completely within 48 hours after hypokalemia was corrected with potassium supplementation. Chorea gradually resolved over a period of 4 weeks. The pathogenesis of TPP and chorea in hyperthyroidism was reviewed herein. In addition, this report highlights a clinical importance for awareness of these neurological complications in children with hyperthyroidism, since they may be the only presenting symptoms of hyperthyroidism and could be confusing with the diagnosis of genuine neuromuscular disorders.
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页码:298 / 301
页数:4
相关论文
共 17 条
  • [1] A case of thyrotoxicosis with chorea: association with anti-phospholipid antibody
    Adcock, J
    Garrick, R
    Kelly, P
    [J]. JOURNAL OF CLINICAL NEUROSCIENCE, 1999, 6 (02) : 168 - 171
  • [2] Generalized chorea with abnormal 18F-fluorodeoxyglucose positron emission tomography findings in a patient with hyperthyroidism
    Chung, Eun Joo
    Bae, Sang Kyun
    Kim, Sang Jin
    [J]. CLINICAL NEUROLOGY AND NEUROSURGERY, 2013, 115 (01) : 108 - 109
  • [3] THYROTOXICOSIS PRESENTING WITH CHOREOATHETOSIS AND SEVERE MYOPATHY
    CLEMENTS, MR
    HAMILTON, DV
    SIKLOS, P
    [J]. JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, 1981, 74 (06) : 459 - 460
  • [4] Reversible chorea in association with graves' disease and Moyamoya syndrome
    Garcin, Beatrice
    Louissaint, Taina
    Hosseini, Hassan
    Blanc, Raphael
    Fenelon, Gilles
    [J]. MOVEMENT DISORDERS, 2008, 23 (04) : 620 - 622
  • [5] Efficacy of propranolol in hyperthyroid-induced chorea: A case report
    Hayashi, R
    Hashimoto, T
    Tako, K
    [J]. MOVEMENT DISORDERS, 2003, 18 (09) : 1073 - 1076
  • [6] Clinical review: Thyrotoxic periodic paralysis: A diagnostic challenge
    Kung, Annie W. C.
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2006, 91 (07) : 2490 - 2495
  • [7] Rising Serum Thyroxine Levels and Chorea in Graves' Disease
    Leblicq, Coralie
    Duval, Michel
    Carmant, Lionel
    Van Vliet, Guy
    Alos, Nathalie
    [J]. PEDIATRICS, 2013, 131 (02) : E616 - E619
  • [8] Mechanism of Thyrotoxic Periodic Paralysis
    Lin, Shih-Hua
    Huang, Chou-Long
    [J]. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2012, 23 (06): : 985 - 988
  • [9] Hashitoxicosis in children: Clinical features and natural history
    Nabhan, ZM
    Kreher, NC
    Eugster, FA
    [J]. JOURNAL OF PEDIATRICS, 2005, 146 (04) : 533 - 536
  • [10] Thyroid-Related Neurological Disorders and Complications in Children
    Nandi-Munshi, Debika
    Taplin, Craig E.
    [J]. PEDIATRIC NEUROLOGY, 2015, 52 (04) : 373 - 382