Ellipsometry study on gold-nanoparticle-coated gold thin film for biosensing application

被引：24

作者：

Moirangthem, Rakesh Singh ^{[1
,2
,3
]}

Chang, Yia-Chung ^{[1
]}

Wei, Pei-Kuen ^{[1
]}

机构：

[1] Acad Sinica, Res Ctr Appl Sci, Taipei 115, Taiwan

[2] Natl Tsing Hua Univ, Dept Engn & Syst Sci, Hsinchu 300, Taiwan

[3] Acad Sinica, Taiwan Int Grad Program, Nano Sci & Technol Program, Taipei 115, Taiwan

来源：

BIOMEDICAL OPTICS EXPRESS | 2011年 / 2卷 / 09期

关键词：

SURFACE-PLASMON-RESONANCE; INTERNAL-REFLECTION ELLIPSOMETRY; BOVINE SERUM-ALBUMIN; SENSOR; LAYERS;

D O I：

10.1364/BOE.2.002569

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The amplified plasmonic response from various distributions of gold nanoparticles (AuNPs) coated on top of gold thin film was studied via ellipsometry under total internal reflection mode. The surface plasmon resonance dip can be tuned from the visible to near infrared by simply varying the AuNP concentration. Theoretical modeling based on effective medium theory with a multi-slice model has been employed to fit the experimental results. Additionally, this experimental tool has been further extended to study bio-molecular interactions with metal surfaces as well as in studying protein-protein interaction without any labeling. Hence, this technique could provide a non-destructive way of designing tunable label-free optical biosensors with very high sensitivity. (C) 2010 Optical Society of America

引用

页码：2569 / 2576

页数：8

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