Immunolocalization of steroidogenic enzymes in the fetal, neonatal and adult testis of the Shiba goat

被引：19

作者：

Weng, Q

Medan, MS

Ren, LQ

Watanabe, G

Tsubota, T

Taya, K

机构：

[1] Tokyo Univ Agr & Technol, Dept Vet Med, Vet Physiol Lab, Fac Agr, Fuchu, Tokyo 1838509, Japan

[2] Beijing Forestry Univ, Fac Biol Sci & Technol, Beijing 100083, Peoples R China

[3] Suez Canal Univ, Fac Med Vet, Dept Theriogenol, Ismailia, Egypt

[4] Gifu Univ, United Grad Sch Vet Sci, Dept Vet Basic Sci, Gifu 5011193, Japan

[5] Gifu Univ, Fac Appl Biol Sci, Dept Vet Med, Lab Zoo & Wildlife Med, Gifu 5011193, Japan

来源：

EXPERIMENTAL ANIMALS | 2005年 / 54卷 / 05期

关键词：

goat testes; immunohistochemistry; steroidogenic enzymes;

D O I：

10.1538/expanim.54.451

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The localizations of steroidogenic enzymes (P450scc, 3 beta HSD, P450c17 and P450arom) in testes of Shiba goats were investigated by immunohistochemistry. P450scc, 3 beta HSD, P450c17 and P450arom were detected in all Leydig cells of adults. P450scc and P450c17 were observed in most Leydig cells in the fetus (90 days) and neonate (15 days). 3 beta HSD and P450arom were found in some Leydig cells of the fetus with weak immunostaining but the numbers of immunopositive Leydig cells and intense immunostaining were increased in Leydig cells of the neonate. These results suggest that Shiba goat testes have the ability to synthesize progestin, androgen and estrogen in the fetus, neonate and adult, and synthesis of these steroid hormones showed an age-related rise.

引用

页码：451 / 454

页数：4

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