Chitosan for Tissue Engineering

被引：72

作者：

Kim, Chun-Ho ^{[1
]}

Park, Sang Jun ^{[1
]}

Yang, Dae Hyeok ^{[2
]}

Chun, Heung Jae ^{[3
]}

机构：

[1] Korea Inst Radiol & Med Sci, Lab Tissue Engn, Seoul, South Korea

[2] Catholic Univ Korea, Inst Cell & Tissue Engn, Coll Med, Seoul, South Korea

[3] Catholic Univ Korea, Inst Cell & Tissue Engn, Dept Biomed Sci, Coll Med, Seoul, South Korea

来源：

NOVEL BIOMATERIALS FOR REGENERATIVE MEDICINE | 2018年 / 1077卷

关键词：

Chitosan; Tissue engineering; Scaffold; Regeneration; Skin; Bone; Cartilage; GROWTH-FACTOR; IN-VITRO; ARTICULAR CHONDROCYTES; POLY(VINYL ALCOHOL); CELL-ADHESION; STEM-CELLS; SCAFFOLDS; CHITIN; EXPRESSION; PROTEIN;

D O I：

10.1007/978-981-13-0947-2_25

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Chitosan, a deacetylated chitin, is one of the few natural polymers similar to glycosamino-glycans (GAGs) widely distributed throughout connective tissues. It has been believed that the excellent biocompatibility of chitosan is largely attributed to this structural similarity. Chitosan is also known to possess biodegradability, antimicrobial activity and low toxicity and immunogenicity which are essential for scaffolds. In addition, the existence of free amine groups in its backbone chain enables further chemical modifications to create the additional biomedical functionality. For these reasons, chitosan has found a tremendous variety of biomedical applications in recent years. This chapter introduces the basic contents of chitosan and discusses its applications to artificial skin, artificial bone, and artificial cartilage in tissue engineering purpose.

引用

页码：475 / 485

页数：11

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