Chitosan for Tissue Engineering

被引：72

作者：

Kim, Chun-Ho ^{[1
]}

Park, Sang Jun ^{[1
]}

Yang, Dae Hyeok ^{[2
]}

Chun, Heung Jae ^{[3
]}

机构：

[1] Korea Inst Radiol & Med Sci, Lab Tissue Engn, Seoul, South Korea

[2] Catholic Univ Korea, Inst Cell & Tissue Engn, Coll Med, Seoul, South Korea

[3] Catholic Univ Korea, Inst Cell & Tissue Engn, Dept Biomed Sci, Coll Med, Seoul, South Korea

来源：

NOVEL BIOMATERIALS FOR REGENERATIVE MEDICINE | 2018年 / 1077卷

关键词：

Chitosan; Tissue engineering; Scaffold; Regeneration; Skin; Bone; Cartilage; GROWTH-FACTOR; IN-VITRO; ARTICULAR CHONDROCYTES; POLY(VINYL ALCOHOL); CELL-ADHESION; STEM-CELLS; SCAFFOLDS; CHITIN; EXPRESSION; PROTEIN;

D O I：

10.1007/978-981-13-0947-2_25

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Chitosan, a deacetylated chitin, is one of the few natural polymers similar to glycosamino-glycans (GAGs) widely distributed throughout connective tissues. It has been believed that the excellent biocompatibility of chitosan is largely attributed to this structural similarity. Chitosan is also known to possess biodegradability, antimicrobial activity and low toxicity and immunogenicity which are essential for scaffolds. In addition, the existence of free amine groups in its backbone chain enables further chemical modifications to create the additional biomedical functionality. For these reasons, chitosan has found a tremendous variety of biomedical applications in recent years. This chapter introduces the basic contents of chitosan and discusses its applications to artificial skin, artificial bone, and artificial cartilage in tissue engineering purpose.

引用

页码：475 / 485

页数：11

共 78 条

[1]

Ahmadi F, 2015, RES PHARM SCI, V10, P1

[2] STUDIES ON CHITOSAN .3. EVIDENCE FOR THE PRESENCE OF RANDOM AND BLOCK COPOLYMER STRUCTURES IN PARTIALLY N-ACETYLATED CHITOSANS [J].

AIBA, S .

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 1991, 13 (01) :40-44

[3] An investigation on burn wound healing in rats with chitosan gel formulation containing epidermal growth factor [J].

Alemdaroglu, C ;

Degim, Z ;

Çelebi, N ;

Zor, F ;

Öztürk, S ;

Erdogan, D .

BURNS, 2006, 32 (03) :319-327

[4] IFATS Collection: Human Adipose-Derived Stem Cells Seeded on a Silk Fibroin-Chitosan Scaffold Enhance Wound Repair in a Murine Soft Tissue Injury Model [J].

Altman, Andrew M. ;

Yan, Yasheng ;

Matthias, Nadine ;

Bai, Xiaowen ;

Rios, Carmen ;

Mathur, Anshu B. ;

Song, Yao-Hua ;

Alt, Eckhard U. .

STEM CELLS, 2009, 27 (01) :250-258

[5]

[Anonymous], BIOPOLYMERS RENEWABL

[6] Basic science of articular cartilage repair [J].

Athanasiou, KA ;

Shah, AR ;

Hernandez, RJ ;

LeBaron, RG .

CLINICS IN SPORTS MEDICINE, 2001, 20 (02) :223-+

[7] Nanofiber technology: Designing the next generation of tissue engineering scaffolds [J].

Barnes, Catherine P. ;

Sell, Scott A. ;

Boland, Eugene D. ;

Simpson, David G. ;

Bowlin, Gary L. .

ADVANCED DRUG DELIVERY REVIEWS, 2007, 59 (14) :1413-1433

[8]

Bernhard P, 2003, TISSUE ENG

[9] Recent advances in hyaluronic acid based therapy for osteoarthritis [J].

Bowman, Steven ;

Awad, Mohamed E. ;

Hamrick, Mark W. ;

Hunter, Monte ;

Fulzele, Sadanand .

CLINICAL AND TRANSLATIONAL MEDICINE, 2018, 7

[10] Influence of the degree of acetylation on some biological properties of chitosan films [J].

Chatelet, C ;

Damour, O ;

Domard, A .

BIOMATERIALS, 2001, 22 (03) :261-268

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