Gold Nanoparticles in Chemical and Biological Sensing

被引:3820
作者
Saha, Krishnendu [1 ]
Agasti, Sarit S. [1 ]
Kim, Chaekyu [1 ]
Li, Xiaoning [1 ]
Rotello, Vincent M. [1 ]
机构
[1] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA
基金
美国国家科学基金会;
关键词
SURFACE-PLASMON RESONANCE; GLASSY-CARBON ELECTRODE; QUARTZ-CRYSTAL-MICROBALANCE; INDIUM-TIN OXIDE; HYDROGEN-PEROXIDE BIOSENSOR; ENHANCED RAMAN-SCATTERING; FUNCTIONALIZED AU NANOPARTICLES; SIZE-CONTROLLED SYNTHESIS; SELF-ASSEMBLED MONOLAYER; ONE-STEP SYNTHESIS;
D O I
10.1021/cr2001178
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A study was conducted to demonstrate the use of gold nanoparticles (AuNP) in chemical and biological sensing. AuNPs possessed distinct physical and chemical attributes that made them excellent scaffolds for the fabrication of novel chemical and biological sensors. AuNPs were synthesized in a straightforward manner and made highly stable, while possessing unique optoelectronic properties and providing high surface-to-volume ratio with excellent biocompatibility using appropriate ligands. These synthetic routes and properties of AuNPs made them excellent probes for different sensing strategies. A variety of other ligands had been used to passivate and functionalize AuNPs, while most AuNP functionalization had been done using thiol or thiolated ligands.
引用
收藏
页码:2739 / 2779
页数:41
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