Coordination polymer hybridized Au nanocages: a nanoplatform for dual-modality imaging guided near-infrared driven photothermal therapy in vivo

被引：10

作者：

Yan, Congyang

Cui, Lili

Yang, Qi

Zhou, Xiaobao

Pan, Lixing

Zhang, Xiaofen

Yang, Hong ^{[1
]}

Zhou, Zhiguo

Yang, Shiping ^{[1
]}

机构：

[1] Shanghai Normal Univ, Shanghai Key Lab Rare Earth Funct Mat, Minist Educ, Key Lab Resource Chem, Shanghai 200234, Peoples R China

来源：

JOURNAL OF MATERIALS CHEMISTRY B | 2017年 / 5卷 / 44期

基金：

中国国家自然科学基金;

关键词：

SINGLET OXYGEN; AG NANOCUBES; NANOPARTICLES; GOLD; DELIVERY; AGENT; NM;

D O I：

10.1039/c7tb02302b

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Coordination polymer hybridized Au nanocages (AuNC@CPs) were prepared via a dialysis process by combining Au nanocages with a coordination polymer, which was derived from (pq)(2)Ir(Hdcbpy) and Dy(OOCCH3)(3). After hybridization, the localized surface plasmon resonance (LSPR) peak of the AuNC@CPs exhibited an evident red shift in comparison with that of the Au nanocages, which was due to a variation in the dielectric constant caused by the coordination polymer. Notably, inspired by their excellent photothermal, photoacoustic, and magnetic properties in solution, AuNC@CPs were used for near-infrared (NIR)-driven photothermal therapy (PTT) guided by photoacoustic (PA) and magnetic resonance (MR) imaging in vivo. Owing to their remarkable performance, the AuNC@CPs would represent promising nanoprobes for theranostics.

引用

页码：8761 / 8769

页数：9

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