The central noradrenaline system and memory consolidation

被引:22
作者
Kobayashi, K [1 ]
Yasoshima, Y [1 ]
机构
[1] Fukushima Med Univ, Sch Med, Inst Biomed Sci, Dept Mol Genet, Fukushima 9601297, Japan
关键词
noradrenaline; adrenergic receptor; conditioned learning; long-term memory; memory consolidation;
D O I
10.1177/107385840100700506
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Long-term memory requires de novo protein synthesis and gene expression, which are mediated by certain intracellular signaling pathways. The noradrenaline (NA) system in the CNS is involved in a wide variety of neurological and psychological functions. In addition to previous pharmacological studies, a recent molecular genetic approach provides behavioral evidence for an essential role of the central NA system in long-term memory formation, particularly in memory consolidation. The potential cellular and molecular mechanisms underlying memory formation mediated by NA are discussed.
引用
收藏
页码:371 / 376
页数:6
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