Computational Molecular Design of Drug Delivery Vehicles for Anti-HIV Microbicides

被引：0
|
作者：
Wilson, Taylor [1 ]
Markey, Amber [2 ]
Camarda, Kyle V. [1 ]
Kieweg, Sarah [3 ,4 ]
机构：
[1] Univ Kansas, Dept Chem & Petr Engn, Lawrence, KS 66049 USA
[2] Univ Kansas, Bioengn Grad Program, Lawrence, KS 66049 USA
[3] Univ Kansas, Dept Mech Engn, Lawrence, KS 66049 USA
[4] Univ Kansas, Dept Obstet & Gynecol, Lawrence, KS 66049 USA
来源：
21ST EUROPEAN SYMPOSIUM ON COMPUTER AIDED PROCESS ENGINEERING | 2011年 / 29卷
关键词：
Molecular Design; Drug Delivery; HIV Prevention; Microbicides;
D O I：
暂无
中图分类号：
TP39 [计算机的应用];
学科分类号：
081203 ; 0835 ;
摘要：
This project seeks to develop a computational design method for novel polymer gels for anti-HIV microbicide delivery. These polymeric liquids need to be specifically designed to meet a set of physiochemical property requirements. A predictive structure-property model was created by regressing experimental property data for a set of representative polymeric vehicles with structural descriptors. The model can next be integrated within an optimization formulation to design novel gels for microbicide delivery applications.
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页码：1480 / 1484
页数：5
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