Relapse Versus Reinfection: Surveillance of Clostridium difficile Infection

被引:68
作者
Kamboj, Mini [1 ,2 ]
Khosa, Perminder [2 ]
Kaltsas, Anna [1 ]
Babady, N. Esther [3 ]
Son, Crystal [2 ]
Sepkowitz, Kent A. [1 ,2 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Infect Dis Serv, New York, NY 10065 USA
[2] Mem Sloan Kettering Canc Ctr, Dept Med, New York, NY 10065 USA
[3] Mem Sloan Kettering Canc Ctr, Microbiol Serv, Dept Clin Labs, New York, NY 10065 USA
关键词
MOLECULAR ANALYSIS; DIARRHEA; RECURRENCES; EPIDEMIC; DISEASE; STRAIN;
D O I
10.1093/cid/cir643
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Molecular typing was used to examine surveillance definitions for recurrent Clostridium difficile-associated diarrhea. Among 102 patients, 85 had a second episode within 8 weeks, 88% of which were relapses. Of 49 second episodes occurring after > 8 weeks, 65% were relapses. Categorization of a recurrent episode occurring after >8 weeks as a new infection may misrepresent the majority of episodes for surveillance.
引用
收藏
页码:1003 / 1006
页数:4
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