The safety and efficacy of percutaneous vertebroplasty for patients over 90years old

被引:17
作者
Kamei, Shunsuke [1 ]
Noguchi, Tomoyuki [1 ]
Shida, Yoshitaka [1 ]
Okafuji, Takashi [1 ]
Yokoyama, Kota [1 ]
Uchiyama, Fumiya [1 ]
Nakatake, Hiroshi [1 ]
Tajima, Tsuyoshi [1 ]
机构
[1] Natl Ctr Global Hlth & Med, Dept Radiol, Shinjuku Ku, 1-21-1 Toyama, Tokyo 1628655, Japan
基金
日本学术振兴会;
关键词
Vertebroplasty; Elderly patient; Decubitus position; Prophylactic treatment; VERTEBRAL COMPRESSION FRACTURES; RANDOMIZED-TRIAL; KYPHOPLASTY;
D O I
10.1007/s11604-018-0797-1
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
ObjectiveTo retrospectively analyze the safety and efficacy of percutaneous vertebroplasty (PVP) for patients aged 90 or over.Materials and methodsWe analyzed 130 consecutive patients with osteoporotic vertebral fractures who underwent a first-time PVP between May 2015 and September 2017 at our institution. We divided them into the elder patient group aged 90years or over (n=21) and the younger patient group under 90years (n=109). We compared the two groups' background, treatments, and outcomes using univariate analyzes and the log rank test.ResultsA significant difference was observed in dementia (19% in the younger group vs. 48% in the elder group, p<0.01). No significant difference was revealed in the procedure time or the rate of complications. The post-PVP mobility function and the pain level were significantly improved compared to before PVP in both groups (p<0.01 each). No significant differences were observed between the two groups in the recurrence of vertebral fracture after treatment (17% vs. 14%) or the 1-year survival rate (79% vs. 86%), respectively.ConclusionThe results of our analyzes suggested that a PVP can safely and effectively contribute to pain relief as well as the restoration of ambulation for patients aged 90 or over.
引用
收藏
页码:178 / 185
页数:8
相关论文
共 21 条
[1]   Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective [J].
Baumgart, Matthew ;
Snyder, Heather M. ;
Carrillo, Maria C. ;
Fazio, Sam ;
Kim, Hye ;
Johns, Harry .
ALZHEIMERS & DEMENTIA, 2015, 11 (06) :718-726
[2]   Kyphoplasty for Vertebral Augmentation in the Elderly With Osteoporotic Vertebral Compression Fractures: Scenarios and Review of Recent Studies [J].
Bednar, Timothy ;
Heyde, Christoph E. ;
Bednar, Grace ;
Nguyen, David ;
Volpi, Elena ;
Przkora, Rene .
CLINICAL THERAPEUTICS, 2013, 35 (11) :1721-1727
[4]   A Randomized Trial of Vertebroplasty for Painful Osteoporotic Vertebral Fractures [J].
Buchbinder, Rachelle ;
Osborne, Richard H. ;
Ebeling, Peter R. ;
Wark, John D. ;
Mitchell, Peter ;
Wriedt, Chris ;
Graves, Stephen ;
Staples, Margaret P. ;
Murphy, Bridie .
NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (06) :557-568
[5]   Safety and efficacy of vertebroplasty for acute painful osteoporotic fractures (VAPOUR): a multicentre, randomised, double-blind, placebo-controlled trial [J].
Clark, William ;
Bird, Paul ;
Gonski, Peter ;
Diamond, Terrence H. ;
Smerdely, Peter ;
McNeil, H. Patrick ;
Schlaphoff, Glen ;
Bryant, Carl ;
Barnes, Elizabeth ;
Gebski, Val .
LANCET, 2016, 388 (10052) :1408-1416
[6]   Management of acute osteoporotic vertebral fractures: A nonrandomized trial comparing percutaneous vertebroplasty with conservative therapy [J].
Diamond, TH ;
Champion, B ;
Clark, WA .
AMERICAN JOURNAL OF MEDICINE, 2003, 114 (04) :257-265
[7]   A Randomized Trial Comparing Balloon Kyphoplasty and Vertebroplasty for Vertebral Compression Fractures due to Osteoporosis [J].
Dohm, M. ;
Black, C. M. ;
Dacre, A. ;
Tillman, J. B. ;
Fueredi, G. .
AMERICAN JOURNAL OF NEURORADIOLOGY, 2014, 35 (12) :2227-2236
[8]   Fracture prediction from bone mineral density in Japanese men and women [J].
Fujiwara, S ;
Kasagi, F ;
Masunari, N ;
Naito, K ;
Suzuki, G ;
Fukunaga, M .
JOURNAL OF BONE AND MINERAL RESEARCH, 2003, 18 (08) :1547-1553
[9]   Kyphoplasty and Vertebroplasty Produce the Same Degree of Height Restoration [J].
Hiwatashi, A. ;
Westesson, P-L A. ;
Yoshiura, T. ;
Noguchi, T. ;
Togao, O. ;
Yamashita, K. ;
Kamano, H. ;
Honda, H. .
AMERICAN JOURNAL OF NEURORADIOLOGY, 2009, 30 (04) :669-673
[10]   A Randomized Trial of Vertebroplasty for Osteoporotic Spinal Fractures [J].
Kallmes, David F. ;
Comstock, Bryan A. ;
Heagerty, Patrick J. ;
Turner, Judith A. ;
Wilson, David J. ;
Diamond, Terry H. ;
Edwards, Richard ;
Gray, Leigh A. ;
Stout, Lydia ;
Owen, Sara ;
Hollingworth, William ;
Ghdoke, Basavaraj ;
Annesley-Williams, Deborah J. ;
Ralston, Stuart H. ;
Jarvik, Jeffrey G. .
NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (06) :569-579