Validation of an Antimicrobial Stewardship-Driven Verigene Blood-Culture Gram-Negative Treatment Algorithm to Improve Appropriateness of Antibiotics

被引：16

作者：

Claeys, Kimberly C. ^{[1
]}

Schlaffer, K. E. ^{[2
]}

Heil, E. L. ^{[1
]}

Leekha, S. ^{[3
,4
]}

Johnson, J. K. ^{[5
]}

机构：

[1] Univ Maryland, Sch Pharm, Dept Pharm Practice & Sci, Baltimore, MD 21201 USA

[2] Univ Maryland Med Syst, Dept Med, Baltimore, MD USA

[3] Univ Maryland, Dept Epidemiol, Sch Med, Baltimore, MD 21201 USA

[4] Dept Publ Hlth, Baltimore, MD USA

[5] Univ Maryland, Dept Pathol, Sch Med, Baltimore, MD 21201 USA

来源：

OPEN FORUM INFECTIOUS DISEASES | 2018年 / 5卷 / 10期

关键词：

diagnostic stewardship; multiplex PCR; rapid diagnostic; STREAM INFECTIONS; KLEBSIELLA-PNEUMONIAE; SEVERE SEPSIS; MORTALITY; OUTCOMES;

D O I：

10.1093/ofid/ofy233

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Rapid diagnostic testing (RDT) allows for early adjustment of antibiotic therapy. This study examined the potential impact of a stewardship-driven antibiotic treatment algorithm, incorporating RDT into the management of Gram-negative bacteremia. The proposed algorithm would have resulted in 88.4% of cases receiving appropriate antibiotic therapy versus 78.1% by standard of care (P = .014).

引用

页数：3

共 13 条

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