Heterogeneity of the PorB protein in serotype 22 Neisseria meningitidis

被引:12
作者
Urwin, R
Fox, AJ
Musilek, M
Kriz, P
Maiden, MCJ
机构
[1] Univ Oxford, Dept Zool, Wellcome Trust Ctr Epidemiol Infect Dis, Oxford OX1 3PS, England
[2] Withington Hosp, Publ Hlth Lab, Manchester M20 2LR, Lancs, England
[3] NIPH, Natl Reference Lab Meningococcal Infect, Prague, Czech Republic
基金
英国惠康基金;
关键词
D O I
10.1128/JCM.36.12.3680-3682.1998
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The genetic diversity of porB genes from meningococcal isolates characterized as serotype 22 was investigated by gene sequencing. This procedure identified seven distinct porB sequences, demonstrating variation in the PorB protein recognized by the serotype 22 monoclonal antibody. This is consistent with the genetic heterogeneity of serotype 22 meningococci reported previously.
引用
收藏
页码:3680 / 3682
页数:3
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