RUNX3 Expression Is an Independent Prognostic Factor in Cytogenetically Abnormal Adult Acute Myeloid Leukemia (AML) Patients with Wild-Type FLT3

被引:0
|
作者
Kwan, Tsz-Ki [1 ]
Cheng, Chi-Keung [1 ]
Cheng, Suk-Hang [1 ]
Chan, Natalie P. H. [1 ]
Ip, Rosalina [1 ]
Wong, Raymond S. M. [2 ]
Yip, Sze-Fai [3 ]
Li, Chi-Kong [4 ]
Ng, Margaret H. L. [1 ]
机构
[1] Chinese Univ Hong Kong, Dept Anat & Cellular Pathol, Hong Kong, Hong Kong, Peoples R China
[2] Prince Wales Hosp, Dept Med & Therapeut, Hong Kong, Hong Kong, Peoples R China
[3] Tuen Mun Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China
[4] Prince Wales Hosp, Children Canc Ctr, Hong Kong, Hong Kong, Peoples R China
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:697 / 698
页数:2
相关论文
共 50 条
  • [1] Evaluation of Emergent FLT3 Mutations (FLT3m) at Relapse in Patients (Pts) with Wild-Type FLT3 Acute Myeloid Leukemia (AML)
    Haddad, Fadi
    Medawar, Georgio
    Kanagal-Shamanna, Rashmi
    Alvarez, Hector
    Loghavi, Sanam
    Daver, Naval
    Pierce, Sherry A.
    Jabbour, Elias
    Kadia, Tapan M.
    Short, Nicholas
    DiNardo, Courtney D.
    Borthakur, Gautam
    Abbas, Hussein A.
    Pemmaraju, Naveen
    Garcia-Manero, Guillermo
    Ravandi, Farhad
    Kantarjian, Hagop
    Yilmaz, Musa
    BLOOD, 2022, 140 : 3196 - 3198
  • [2] Gene expression profiling identifies FLT3 mutation-like cases in wild-type FLT3 acute myeloid leukemia
    Mosquera Orgueira, Adrian
    Peleteiro Raindo, Andres
    Cid Lopez, Miguel
    Antelo Rodriguez, Beatriz
    Diaz Arias, Jose Angel
    Ferreiro Ferro, Roi
    Alonso Vence, Natalia
    Bendana Lopez, Angeles
    Abuin Blanco, Aitor
    Bao Perez, Laura
    Melero Valentin, Paula
    Gonzalez Perez, Marta Sonia
    Cerchione, Claudio
    Martinelli, Giovanni
    Montesinos Fernandez, Pau
    Perez Encinas, Manuel Mateo
    Bello Lopez, Jose Luis
    PLOS ONE, 2021, 16 (02):
  • [3] More on prognostic significance of FLT3/ITD size in acute myeloid leukemia (AML)
    Kusec, Rajko
    Jaksic, Ozren
    Ostojic, Slobodanka
    Kardum-Skelin, Ika
    Vrhovac, Radovan
    Jaksic, Branimir
    BLOOD, 2006, 108 (01) : 405 - 406
  • [4] Prognostic Impact of Mutant to Wild-Type Ratio and Insertion Site in Acute Myeloid Leukemia with FLT3 Internal Tandem Duplication
    Kayser, Sabine
    Schlenk, Richard F.
    Krauter, Juergen
    Koehne, Claus-Henning
    Germing, Ulrich
    Held, Gerhard
    Horst, Heinz A.
    Ringhoffer, Mark
    von Lilienfeld-Toal, Marie
    Rummel, Mathias J.
    Goetze, Katharina
    Nachbaur, David
    Schlegelberger, Brigitte
    Goehring, Gudrun
    Salih, Helmut R.
    Martin, Hans
    Herr, Wolfgang
    Luebbert, Michael
    Salwender, Hans-Juergen
    Erdmann, Patricia
    Paschka, Peter
    Gaidzik, Verena I.
    Teleanu, Veronica
    Spaeth, Daniela
    Ganser, Arnold
    Fischer, Thomas
    Doehner, Hartmut
    Doehner, Konstanze
    BLOOD, 2012, 120 (21)
  • [5] Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells
    Chen, Fangli
    Ishikawa, Yuichi
    Akashi, Akimi
    Naoe, Tomoki
    Kiyoi, Hitoshi
    ONCOTARGET, 2016, 7 (30) : 47018 - 47032
  • [6] The presence of FLT3/ITD mutations is an independent prognostic factor in acute myeloid leukemia patients with normal karyotype.
    Kim, YK
    Lee, JJ
    Lee, YR
    Lee, IK
    Kim, HN
    Kim, NY
    Park, KS
    Yang, DH
    Park, MR
    Kim, HJ
    BLOOD, 2004, 104 (11) : 822A - 822A
  • [7] RUNX1 mutation and elevated FLT3 gene expression cooperates to induce inferior prognosis in cytogenetically normal acute myeloid leukemia patients
    Rehman, Atia
    Akram, Afia Muhammad
    Chaudhary, Asma
    Sheikh, Nadeem
    Hussain, Zawar
    Alsanie, Walaa F.
    Rehman, Rahat Abdul
    Hameed, Naila
    Saleem, Tayyaba
    Zafar, Amjad
    Absar, Muhammad
    Iqbal, Zafar
    Alhazmi, Alaa
    Baeshen, Hosam Ali
    Mohammedsaleh, Zuhair M.
    Qamer, Samina
    Sayed, Samy
    Gaber, Ahmed
    SAUDI JOURNAL OF BIOLOGICAL SCIENCES, 2021, 28 (09) : 4845 - 4851
  • [8] IMPACT OF FLT3 RECEPTOR EXPRESSION ON CLINICAL OUTCOME OF ADULT ACUTE MYELOID LEUKEMIA PATIENTS
    Kandeel, Eman
    El Sayed, Ghada
    ELsharkawy, Nahla
    Kamel, Azza
    Negm, Dalia
    Ibrahim, Dalia
    INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 2018, 40 : 65 - 65
  • [9] AML, acute myeloid leukemia, FLT3 gene mutation Specific Features of the FLT3+Acute Myeloid Leukemia Course
    Radzhabova, Asiyat M.
    Martynkevich, Irina S.
    Motyko, Ekaterina V.
    Polushkina, Lubov B.
    Bakay, Marina P.
    Kuzyaeva, Anastasiya A.
    Voloshin, Sergey V.
    Potihonova, Nadezhda
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2022, 22 : S228 - S229
  • [10] Prognostic implications of the presence of FLT3 mutations in patients with acute myeloid leukemia
    Kottaridis, PD
    Gale, RE
    Linch, DC
    LEUKEMIA & LYMPHOMA, 2003, 44 (06) : 905 - 913