Bioinspired Polymeric Nanocomposites for Regenerative Medicine

被引:109
作者
Carrow, James K. [1 ]
Gaharwar, Akhilesh K. [1 ,2 ]
机构
[1] Texas A&M Univ, Dept Biomed Engn, College Stn, TX 77843 USA
[2] Texas A&M Univ, Dept Mat Sci & Engn, College Stn, TX 77843 USA
关键词
bioinspired structures; hydrogels; nanomaterials; polymeric nanocomposites; tissue engineering; MESENCHYMAL STEM-CELLS; SIMULATED BODY-FLUID; TISSUE-ENGINEERING SCAFFOLDS; CROSS-LINKED PEO; MECHANICAL-PROPERTIES; OSTEOGENIC DIFFERENTIATION; BIOMEDICAL APPLICATIONS; SILICATE NANOPLATELETS; POLY(ETHYLENE GLYCOL); SURFACE MODIFICATION;
D O I
10.1002/macp.201400427
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
The design and fabrication of bioinspired nanomaterials for tissue-engineering applications requires a fundamental understanding of the interactions between polymers, nanostructures, and cells. Most biomimetic polymeric nanocomposites consist of two or more types of polymers or of polymers combined with different nanomaterials to obtain composite structures with desired properties. In this Talents & Trends article, the focus is on bioinspired polymeric nanocomposites surrounding three major strategies. Firstly, biomimetic structures composed of a fibrous architecture are discussed. Secondly, the emerging trends in designing complex nanocomposites with multiple functionalities are assessed. Finally, some of the most critical challenges that come with the design and fabrication are highlighted in bioprinting. Finally, the emerging trends in the field of bioinspired polymeric nanocomposites are highlighted.
引用
收藏
页码:248 / 264
页数:17
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