Fluid Dynamics of Respiratory Infectious Diseases

被引:92
作者
Bourouiba, Lydia [1 ]
机构
[1] MIT, Fluid Dynam Dis Transmiss Lab, Cambridge, MA 02139 USA
来源
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 23, 2021 | 2021年 / 23卷
基金
美国国家科学基金会; 英国惠康基金;
关键词
host-to-host transmission; infectious diseases; masks; ventilation; aerosols; airborne; social distancing; multiphase flows; turbulence; fragmentation; COVID-19; HEALTH-CARE WORKERS; SIZE DISTRIBUTION; AIRBORNE TRANSMISSION; PARTICLE-SIZE; UNITED-STATES; DROP IMPACT; INFLUENZA; TRANSPORT; AEROSOLS; TUBERCULOSIS;
D O I
10.1146/annurev-bioeng-111820-025044
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The host-to-host transmission of respiratory infectious diseases is fundamentally enabled by the interaction of pathogens with a variety of fluids (gas or liquid) that shape pathogen encapsulation and emission, transport and persistence in the environment, and new host invasion and infection. Deciphering the mechanisms and fluid properties that govern and promote these steps of pathogen transmission will enable better risk assessment and infection control strategies, and may reveal previously underappreciated ways in which the pathogens might actually adapt to or manipulate the physical and chemical characteristics of these carrier fluids to benefit their own transmission. In this article, I review our current understanding of the mechanisms shaping the fluid dynamics of respiratory infectious diseases.
引用
收藏
页码:547 / 577
页数:31
相关论文
共 134 条
[1]   Speech can produce jet-like transport relevant to asymptomatic spreading of virus [J].
Abkarian, Manouk ;
Mendez, Simon ;
Xue, Nan ;
Yang, Fan ;
Stone, Howard A. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (41) :25237-25245
[2]   Natural sources and experimental generation of bioaerosols: Challenges and perspectives [J].
Alsved, Malin ;
Bourouiba, Lydia ;
Duchaine, Caroline ;
Londahl, Jakob ;
Marr, Linsey C. ;
Parker, Simon T. ;
Prussin, Aaron J., II ;
Thomas, Richard J. .
AEROSOL SCIENCE AND TECHNOLOGY, 2020, 54 (05) :547-571
[3]  
[Anonymous], 2019, Middle East respiratory syndrome (MERS)
[4]  
[Anonymous], 2001, Aerosol Measurement
[5]  
[Anonymous], 1876, Cohns Beitrge zur Biologie der Pflanzen
[6]   Aerosol emission and superemission during human speech increase with voice loudness [J].
Asadi, Sima ;
Wexler, Anthony S. ;
Cappa, Christopher D. ;
Barreda, Santiago ;
Bouvier, Nicole M. ;
Ristenpart, William D. .
SCIENTIFIC REPORTS, 2019, 9 (1)
[7]  
Ashgriz N, 2011, HDB ATOMIZATION THEO
[8]   Face coverings and mask to minimise droplet dispersion and aerosolisation: a video case study [J].
Bahl, Prateek ;
Bhattacharjee, Shovon ;
de Silva, Charitha ;
Chughtai, Abrar Ahmad ;
Doolan, Con ;
MacIntyre, C. Raina .
THORAX, 2020, 75 (11) :1024-1025
[9]   Host-to-host airborne transmission as a multiphase flow problem for science-based social distance guidelines [J].
Balachandar, S. ;
Zaleski, S. ;
Soldati, A. ;
Ahmadi, G. ;
Bourouiba, L. .
INTERNATIONAL JOURNAL OF MULTIPHASE FLOW, 2020, 132
[10]   SURVIVAL OF INFLUENZA-VIRUSES ON ENVIRONMENTAL SURFACES [J].
BEAN, B ;
MOORE, BM ;
STERNER, B ;
PETERSON, LR ;
GERDING, DN ;
BALFOUR, HH .
JOURNAL OF INFECTIOUS DISEASES, 1982, 146 (01) :47-51