Molecular characterization of the first G24P[14] rotavirus strain detected in humans

被引:16
作者
Ward, M. Leanne [1 ]
Mijatovic-Rustempasic, Slavica [1 ]
Roy, Sunando [1 ]
Rungsrisuriyachai, Kunchala [1 ]
Boom, Julie A. [2 ,3 ]
Sahni, Leila C. [2 ]
Baker, Carol J. [2 ,3 ]
Rench, Marcia A. [2 ,3 ]
Wikswo, Mary E. [1 ]
Payne, Daniel C. [1 ]
Parashar, Umesh D. [1 ]
Bowen, Michael D. [1 ]
机构
[1] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Div Viral Dis, Atlanta, GA 30329 USA
[2] Texas Childrens Hosp, Houston, TX 77030 USA
[3] Baylor Coll Med, Houston, TX 77030 USA
关键词
Rotavirus; G24P[14; Bovine; Reassortment; FULL GENOMIC CHARACTERIZATION; GENOTYPE; CLASSIFICATION;
D O I
10.1016/j.meegid.2016.05.033
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Here we report the genome of a novel rotavirus A (RVA) strain detected in a stool sample collected during routine surveillance by the Centers for Disease Control and Prevention's New Vaccine Surveillance Network. The strain, RVA/human-wt/USA/2012741499/2012/G24P[14], has a genomic constellation of G24-P[14]-I2-R2-C2-M2-A3-N2-T9-E2-H3. The VP2, VP3, VP7 and NSP3 genes cluster phylogenetically with bovine strains. The other genes occupy mixed clades containing animal and human strains. Strain RVA/human-wt/USA/2012741499/2012/G24P[14] most likely is the product of interspecies transmission and reassortment events. This is the second report of the G24 genotype and the first report of the G24P[14] genotype combination in humans. Published by Elsevier B.V.
引用
收藏
页码:338 / 342
页数:5
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