Short-Term Oral Nutritional Intervention with Protein and Vitamin D Decreases Falls in Malnourished Older Adults

被引:89
作者
Neelemaat, Floor [1 ,3 ,5 ]
Lips, Paul [2 ,5 ]
Bosmans, Judith E. [4 ,5 ]
Thijs, Abel [3 ]
Seidell, Jaap C. [4 ,5 ]
van Bokhorst-de van der Schueren, Marian A. E. [1 ,3 ,5 ]
机构
[1] Vrije Univ Amsterdam Med Ctr, Dept Nutr & Dietet, NL-1007 MB Amsterdam, Netherlands
[2] Vrije Univ Amsterdam Med Ctr, Endocrinol Sect, NL-1007 MB Amsterdam, Netherlands
[3] Vrije Univ Amsterdam Med Ctr, Dept Internal Med, NL-1007 MB Amsterdam, Netherlands
[4] Vrije Univ Amsterdam, Dept Hlth Sci, Fac Earth & Life Sci, Amsterdam, Netherlands
[5] EMGO Inst Hlth & Care Res, Amsterdam, Netherlands
关键词
falls; elderly patients; nutritional intervention; protein; energy; vitamin D; RCT; BIOELECTRICAL-IMPEDANCE ANALYSIS; RISK-FACTORS; PHYSICAL PERFORMANCE; HOSPITAL DISCHARGE; CONTROLLED-TRIAL; ELDERLY PERSONS; SUPPLEMENTATION; PEOPLE; METAANALYSIS; FRACTURES;
D O I
10.1111/j.1532-5415.2011.03888.x
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
OBJECTIVES: To evaluate the effects of a short-term nutritional intervention with protein and vitamin D on falls in malnourished older adults. DESIGN: Randomized controlled trial. SETTING: From hospital admission until 3 months after discharge. PARTICIPANTS: Malnourished older adults (>= 60) newly admitted to an acute hospital (n = 210). INTERVENTION: Participants were randomized to receive nutritional intervention (energy- and protein-enriched diet, oral nutritional supplements, calcium-vitamin D supplement, telephone counseling by a dietitian) for 3 months after discharge or usual care. MEASUREMENTS: Number of participants who fell, fall incidents, serum 25-hydroxyvitamin D, and dietary intake. Measurements were performed on admission to hospital and 3 months after discharge. RESULTS: Three months after discharge, 10 participants (10%) in the intervention group had fallen at least once, compared with 24 (23%) in the control group (hazard ratio = 0.41, 95% confidence interval (CI) = 0.19-0.86). There were 57 fall incidents (16 in the intervention group; 41 in the control group). A significantly higher intake of energy (280 kcal, 95% CI = 37-524 kcal) and protein (11 g, 95% CI = 1-25 g) and significantly higher serum 25-hydroxyvitamin D levels (10.9 nmol/L, 95% CI = 2.9-18.9 nmol/L) were found in participants in the intervention group than in controls. CONCLUSION: A short-term nutritional intervention consisting of oral nutritional supplements and calcium and vitamin D supplementation and supported by dietetic counseling in malnourished older adults decreases the number of patients who fall and fall incidents. J Am Geriatr Soc 60:691-699, 2012.
引用
收藏
页码:691 / 699
页数:9
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