Air Pollution and Noncommunicable Diseases A Review by the Forum of International Respiratory Societies' Environmental Committee, Part 1: The Damaging Effects of Air Pollution

被引:235
作者
Schraufnagel, Dean E. [1 ]
Balmes, John R. [2 ,3 ]
Cowl, Clayton T. [4 ,5 ]
De Matteis, Sara [6 ]
Jung, Soon-Hee [7 ]
Mortimer, Kevin [8 ]
Perez-Padilla, Rogelio [9 ]
Rice, Mary B. [10 ]
Riojas-Rodriguez, Horacio [11 ]
Sood, Akshay [12 ]
Thurston, George D. [13 ,14 ]
To, Teresa [15 ]
Vanker, Anessa [16 ,17 ]
Wuebbles, Donald J. [18 ]
机构
[1] Univ Illinois, Pulm Crit Care Sleep & Allergy, Chicago, IL USA
[2] Univ Calif San Francisco, Dept Med, San Francisco, CA USA
[3] Univ Calif Berkeley, Sch Publ Hlth, Div Environm Hlth Sci, Berkeley, CA 94720 USA
[4] Mayo Clin, Div Prevent Occupat & Aerosp Med, Rochester, MN USA
[5] Mayo Clin, Div Pulm & Crit Care Med, Rochester, MN USA
[6] Imperial Coll London, Natl Heart & Lung Inst, London, England
[7] Yonsei Univ, Dept Pathol, Wonju Colleage Med, Seoul, South Korea
[8] Univ Liverpool Liverpool Sch Trop Med, Liverpool, Merseyside, England
[9] Natl Inst Resp Dis, Mexico City, DF, Mexico
[10] Harvard Med Sch, Div Pulm Crit Care & Sleep Med, Beth Israel Deaconess Med Ctr, Boston, MA USA
[11] Natl Inst Publ Hlth, Cuernavaca, Morelos, Mexico
[12] Univ New Mexico, Sch Med, Pulm Crit Care & Sleep Med, Albuquerque, NM 87131 USA
[13] NYU, Dept Environm Med, Sch Med, 550 1St Ave, New York, NY 10016 USA
[14] NYU, Sch Med, Dept Populat Hlth, New York, NY USA
[15] Univ Toronto, Hosp Sick Children, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada
[16] Univ Cape Town, Dept Paediat & Child Hlth, Cape Town, South Africa
[17] Univ Cape Town, MRC Unit Child & Adolescent Hlth, Cape Town, South Africa
[18] Univ Illinois, Dept Atmospher Sci, Sch Earth Soc & Environm, 105 S Gregory Ave, Urbana, IL 61801 USA
关键词
air pollution; mechanism of damage; noncommunicable diseases; ADVERSE BIRTH OUTCOMES; PARTICULATE MATTER; MATERNAL EXPOSURE; LUNG-FUNCTION; FETAL-GROWTH; RESIDENTIAL PROXIMITY; INFANT-MORTALITY; INCIDENT ASTHMA; OZONE EXPOSURE; HEALTH;
D O I
10.1016/j.chest.2018.10.042
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Air pollution poses a great environmental risk to health. Outdoor fine particulate matter (particulate matter with an aerodynamic diameter < 2.5 mu m) exposure is the fifth leading risk factor for death in the world, accounting for 4.2 million deaths and > 103 million disability-adjusted life years lost according to the Global Burden of Disease Report. The World Health Organization attributes 3.8 million additional deaths to indoor air pollution. Air pollution can harm acutely, usually manifested by respiratory or cardiac symptoms, as well as chronically, potentially affecting every organ in the body. It can cause, complicate, or exacerbate many adverse health conditions. Tissue damage may result directly from pollutant toxicity because fine and ultrafine particles can gain access to organs, or indirectly through systemic inflammatory processes. Susceptibility is partly under genetic and epigenetic regulation. Although air pollution affects people of all regions, ages, and social groups, it is likely to cause greater illness in those with heavy exposure and greater susceptibility. Persons are more vulnerable to air pollution if they have other illnesses or less social support. Harmful effects occur on a continuum of dosage and even at levels below air quality standards previously considered to be safe.
引用
收藏
页码:409 / 416
页数:8
相关论文
共 66 条
  • [1] [Anonymous], 2016, AMB AIR POLL
  • [2] Allergy and asthma: Effects of the exposure to particulate matter and biological allergens
    Baldacci, S.
    Maio, S.
    Cerrai, S.
    Sarno, G.
    Baiz, N.
    Simoni, M.
    Annesi-Maesano, I.
    Viegi, G.
    [J]. RESPIRATORY MEDICINE, 2015, 109 (09) : 1089 - 1104
  • [3] Activation of Pulmonary Dendritic Cells and Th2-Type Inflammatory Responses on Instillation of Engineered, Environmental Diesel Emission Source or Ambient Air Pollutant Particles in vivo
    Bezemer, Gillina F. G.
    Bauer, Stephen M.
    Oberdoerster, Guenter
    Breysse, Patrick N.
    Pieters, Raymond H. H.
    Georas, Steve N.
    Williams, Marc A.
    [J]. JOURNAL OF INNATE IMMUNITY, 2011, 3 (02) : 150 - 166
  • [4] Prenatal Air Pollution Exposures, DNA Methyl Transferase Genotypes, and Associations with Newborn LINE1 and Alu Methylation and Childhood Blood Pressure and Carotid Intima-Media Thickness in the Children's Health Study
    Breton, Carrie V.
    Yao, Jin
    Millstein, Josh
    Gao, Lu
    Siegmund, Kimberly D.
    Mack, Wendy
    Whitfield-Maxwell, Lora
    Lurmann, Fred
    Hodis, Howard
    Avol, Ed
    Gilliland, Frank D.
    [J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 2016, 124 (12) : 1905 - 1912
  • [5] Genetic Variation in the Glutathione Synthesis Pathway, Air Pollution, and Children's Lung Function Growth
    Breton, Carrie V.
    Salam, Muhammad T.
    Vora, Hita
    Gauderman, W. James
    Gilliland, Frank D.
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2011, 183 (02) : 243 - 248
  • [6] Global estimates of mortality associated with long-term exposure to outdoor fine particulate matter
    Burnett, Richard
    Chen, Hong
    Szyszkowicz, Mieczyslaw
    Fann, Neal
    Hubbell, Bryan
    Pope, C. Arden
    Apte, Joshua S.
    Brauer, Michael
    Cohen, Aaron
    Weichenthal, Scott
    Coggins, Jay
    Di, Qian
    Brunekreef, Bert
    Frostad, Joseph
    Lim, Stephen S.
    Kan, Haidong
    Walker, Katherine D.
    Thurston, George D.
    Hayes, Richard B.
    Lim, Chris C.
    Turner, Michelle C.
    Jerrett, Michael
    Krewski, Daniel
    Gapstur, Susan M.
    Diver, W. Ryan
    Ostro, Bart
    Goldberg, Debbie
    Crouse, Daniel L.
    Martin, Randall V.
    Peters, Paul
    Pinault, Lauren
    Tjepkema, Michael
    van Donkelaar, Aaron
    Villeneuve, Paul J.
    Miller, Anthony B.
    Yin, Peng
    Zhou, Maigeng
    Wang, Lijun
    Janssen, Nicole A. H.
    Marra, Marten
    Atkinson, Richard W.
    Tsang, Hilda
    Thuan Quoc Thach
    Cannon, John B.
    Allen, Ryan T.
    Hart, Jaime E.
    Laden, Francine
    Cesaroni, Giulia
    Forastiere, Francesco
    Weinmayr, Gudrun
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (38) : 9592 - 9597
  • [7] The effects of ozone exposure and associated injury mechanisms on the central nervous system
    Carlos Martinez-Lazcano, Juan
    Gonzalez-Guevara, Edith
    del Carmen Rubio, Maria
    Franco-Perez, Javier
    Custodio, Veronica
    Hernandez-Ceron, Miguel
    Livera, Carlos
    Paz, Carlos
    [J]. REVIEWS IN THE NEUROSCIENCES, 2013, 24 (03) : 337 - 352
  • [8] Traffic-related air pollution and incident asthma in a high-risk birth cohort
    Carlsten, Chris
    Dybuncio, Anne
    Becker, Allan
    Chan-Yeung, Moira
    Brauer, Michael
    [J]. OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2011, 68 (04) : 291 - 295
  • [9] Effect of reductions in biomass fuel exposure on symptoms of sleep apnea in children living in the peruvian andes: A preliminary field study
    Castaneda, Jacqueline L.
    Kheirandish-Gozal, Leila
    Gozal, David
    Accinelli, Roberto A.
    [J]. PEDIATRIC PULMONOLOGY, 2013, 48 (10) : 996 - 999
  • [10] Maternal exposure to ambient air pollution and fetal growth in North-East Scotland: A population-based study using routine ultrasound scans
    Clemens, Tom
    Turner, Steve
    Dibben, Chris
    [J]. ENVIRONMENT INTERNATIONAL, 2017, 107 : 216 - 226