A solid-state 17O NMR study of β-glycine:: High sensitivity of 17O NMR parameters to hydrogen-bonding interactions

被引：6

作者：

Yamada, Kazuhiko ^{[1
,2
]}

Shimizu, Tadashi ^{[1
]}

Yamazaki, Toshio ^{[2
]}

Sato, Akira ^{[1
]}

机构：

[1] Natl Inst Mat Sci, Tsukuba, Ibaraki 3050044, Japan

[2] Yokohama Inst, RIKEN, Yokohama, Kanagawa 2300045, Japan

来源：

CHEMISTRY LETTERS | 2008年 / 37卷 / 04期

关键词：

D O I：

10.1246/cl.2008.472

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We will present a solid-state O-17 NMR study of beta-glycine and demonstrate that O-17 NMR parameters are highly sensitive to the local molecular structures, in particular, hydrogen-bond environments, indicating that, potentially, solid-state O-17 NMR is a powerful tool for investigating the polymorphs of drugs.

引用

页码：472 / 473

页数：2

共 9 条

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