Lung Cancer Imaging: Screening Result and Nodule Management

被引:14
作者
Guerrini, Susanna [1 ]
Del Roscio, Davide [2 ]
Zanoni, Matteo [2 ]
Cameli, Paolo [3 ]
Bargagli, Elena [3 ]
Volterrani, Luca [2 ]
Mazzei, Maria Antonietta [2 ,4 ]
Luzzi, Luca [5 ]
机构
[1] Univ Siena, Azienda Osped Univ Senese, Dept Radiol Sci, Unit Diagnost Imaging, I-53100 Siena, Italy
[2] Univ Siena, Azienda Osped Univ Senese, Unit Diagnost Imaging, Dept Med Surg & Neuro Sci & Radiol Sci, I-53100 Siena, Italy
[3] Univ Siena, Azienda Osped Univ Senese, Dept Med Surg & Neuro Sci, Resp Dis Unit, I-53100 Siena, Italy
[4] SIRM Fdn, Italian Soc Med & Intervent Radiol SIRM, I-20122 Milan, Italy
[5] Univ Siena, Azienda Osped Univ Senese, Dept Med Surg & Neurosci, Lung Transplant Unit, I-53100 Siena, Italy
关键词
lung cancer; prevention; health education; MDCT; lung screening; lung nodule management; FOLLOW-UP; PULMONARY NODULES; DOSE CT; TRIAL; DESIGN; MSCT; RADIOMICS; MORTALITY; PATTERNS; NELSON;
D O I
10.3390/ijerph19042460
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Background: Lung cancer (LC) represents the main cause of cancer-related deaths worldwide, especially because the majority of patients present with an advanced stage of the disease at the time of diagnosis. This systematic review describes the evidence behind screening results and the current guidelines available to manage lung nodules. Methods: This review was guided by the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. The following electronic databases were searched: PubMed, EMBASE, and the Web of Science. Results: Five studies were included in the systematic review. The study cohort included 46,364 patients, and, in this case series, LC was detected in 9028 patients. Among the patients with detected LC, 1261 died of lung cancer, 3153 died of other types of cancers and 4614 died of other causes. Conclusions: This systematic review validates the use of CT in LC screening follow-ups, and bids for future integration and implementation of nodule management protocols to improve LC screening, avoid missed cancers and to reduce the number of unnecessary investigations.
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页数:10
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