Copper-Catalyzed C(sp2)-S Coupling Reactions for the Synthesis of Aryl Dithiocarbamates with Thiuram Disulfide Reagents

被引：116
作者：
Dong, Zhi-Bing [1 ,2 ]
Liu, Xing [1 ]
Bolm, Carsten [2 ]
机构：
[1] Wuhan Inst Technol, Sch Chem & Environm Engn, Wuhan 430205, Hubei, Peoples R China
[2] Rhein Westfal TH Aachen, Inst Organ Chem, Landoltweg 1, D-52056 Aachen, Germany
来源：
ORGANIC LETTERS | 2017年 / 19卷 / 21期
基金：
中国国家自然科学基金;
关键词：
EFFICIENT SYNTHESIS; ANTIFUNGAL ACTIVITY; ONE-POT; CHEMISTRY; ISOTHIOCYANATES; DERIVATIVES;
D O I：
10.1021/acs.orglett.7b02911
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient protocol for the copper-catalyzed preparation of aryl dithiocarbamates from aryl iodides and inexpensive, environmentally benign tetraalkylthiuram disulfides was developed. The features of mild reaction conditions, high yields, and broad substrate scope render this new approach synthetically attractive for the preparation of potentially biologically active compounds.
引用
收藏
页码：5916 / 5919
页数：4
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