Hematologic concerns in extracorporeal membrane oxygenation

被引：49

作者：

Sniderman, Jonathan ^{[1
]}

Monagle, Paul ^{[2
]}

Annich, Gail M. ^{[3
]}

MacLaren, Graeme ^{[1
,4
,5
]}

机构：

[1] Royal Childrens Hosp, Paediat ICU, Melbourne, Vic, Australia

[2] Univ Melbourne, Dept Paediat, Haematol Res Murdoch Childrens Res Inst, Royal Childrens Hosp,Dept Haematol, Melbourne, Vic, Australia

[3] Univ Toronto, Hosp Sick Children, Dept Crit Care Med, Toronto, ON, Canada

[4] Univ Melbourne, Dept Paediat, Parkville, Vic, Australia

[5] Natl Univ Hlth Syst, Cardiothorac ICU, Singapore, Singapore

来源：

RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS | 2020年 / 4卷 / 04期

关键词：

adult; extracorporeal membrane oxygenation; hemolysis; hemorrhage; pediatric; thrombosis; CARDIOPULMONARY BYPASS CIRCUITS; UNFRACTIONATED HEPARIN-THERAPY; ANTITHROMBIN CONCENTRATE USE; DIRECT THROMBIN INHIBITORS; PLASMA-FREE HEMOGLOBIN; NITRIC-OXIDE RELEASE; ACUTE-RENAL-FAILURE; LONG-TERM SURVIVAL; INTRACRANIAL HEMORRHAGE; FOLLOW-UP;

D O I：

10.1002/rth2.12346

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This ISTH "State of the Art" review aims to critically evaluate the hematologic considerations and complications in extracorporeal membrane oxygenation (ECMO). ECMO is experiencing a rapid increase in clinical use, but many questions remain unanswered. The existing literature does not address or explicitly state many pertinent details that may influence hematologic complications and, ultimately, patient outcomes. This review aims to broadly introduce modern ECMO practices, circuit designs, circuit materials, hematologic complications, transfusion-related considerations, age- and size-related differences, and considerations for choosing outcome measures. Relevant studies from the 2019 ISTH Congress in Melbourne, which further advanced our understanding of these processes, will also be highlighted.

引用

页码：455 / 468

页数：14

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